Download PDF
Free download in PDF Antigen and Antibody Objective Type Questions & Answers for competitive exams. These short objective type questions with answers are very important for competitive exams like NEET, AIIMS etc. as well as Board exams. These short solved questions or quizzes are provided by Gkseries.
(21)
Name the class of immunoglobulin which takes part in hypersensitivity reaction?
[A]
IgG
[B]
IgE
[C]
IgA
[D]
IgM
(22)
Fluorescent treponemal antibody test is an example of
[A]
indirect immunofluorescence
[B]
direct immunofluorescence
[C]
both (a) and (b)
[D]
none of these
Answer: indirect immunofluorescence
(23)
Counter-immunoelectrophoresis is used for the detection of
[A]
Meningococcal antigen
[B]
Hepatitis B surface antigen
[C]
Alpha-fetoprotein
[D]
All of these
(24)
Commercially available ELISA kits are used for the detection of
[A]
rotavirus
[B]
hepatitis B surface antigen
[C]
anti-HIV antibodies
[D]
all of these
(25)
Precipitation reaction is relatively less sensitive for the detection of
[A]
antigens
[B]
antigen-antibody complexes
[C]
antibodies
[D]
complement
(26)
All of the following are true of antigen EXCEPT which one of the following?
[A]
They contain epitopes
[B]
They will react with antibodies
[C]
They contain antigenic determinants
[D]
They contain paratopes
Answer: They contain paratopes
(27)
All of the following are true about antibodies, EXCEPT which one?
[A]
They fix complement
[B]
They occur on the surface of B-lymphocyte
[C]
They predominate the primary immune response to antigen
[D]
They are molecule with a single, defined amino acid sequence
Answer: They are molecule with a single, defined amino acid sequence
(28)
Which of the following statements best characterizes an antibody?
[A]
An antibody contains high molecular weight RNA as its basic structure
[B]
An antibody is composed of protein and cannot be distinguished from the albumin fraction of the serum proteins
[C]
An antibody is composed of four identical protein subunits which may be caused to dissociate by treatment with urea
[D]
An antibody contains protein as its major chemical component and its synthesis may be elicited by the administration of a foreign protein or polysaccharide
Answer: An antibody contains protein as its major chemical component and its synthesis may be elicited by the administration of a foreign protein or polysaccharide
(29)
Individuals unable to make the J protein found in certain immunoglobulins would be expected to have frequent infections of the
[A]
brain
[B]
blood
[C]
liver
[D]
intestinal tract
(30)
All of the following are true with respect to IgM antibodies EXCEPT which one
[A]
they fix complement
[B]
they occur on the surface of lymphocytes
[C]
they predominate in the primary response to antigen
[D]
they mediate allergic reaction
Answer: they mediate allergic reaction
31
One principal function of complement is to
[A]
inactivate perforins
[B]
mediate the release of histamine
[C]
Bind antibodies attached to cell surfaces and to lyse these cells
[D]
phagocytize antigens
Answer: Bind antibodies attached to cell surfaces and to lyse these cells
32
The major role of the complement system is to work in conjunction with
[A]
antibodies to lyse cells via the C8 and C9 components
[B]
the major histocompatibility complex for cell recognition
[C]
antibodies to opsonize cells
[D]
the T-cell receptor for production of lymphokines
Answer: antibodies to lyse cells via the C8 and C9 components
33
T-cell antigen receptors are distinguished from antibodies by which of the following
[A]
T-Cell receptors are glycosylated
[B]
T-cell receptors must interact with antigen uniquely presented by other cells but not with free antigen
[C]
T-Cell receptors bind various cytokines
[D]
T-Cell receptors bind complement to lyse cells
Answer: T-cell receptors must interact with antigen uniquely presented by other cells but not with free antigen
34
T-cell receptors or antibodies react with antigens
[A]
because both are made by lymphocytes
[B]
because of complementary of molecular fit of both with antigen
[C]
because both 'have light chain and heavy chain polypeptides
[D]
cause histamine release
Answer: because of complementary of molecular fit of both with antigen
35
The major immunoglobulin family to which a particular immunoglobulin belongs can be determined by sequential analysis of the 110 amino acids beginning from the
[A]
Amino terminus of the light chain
[B]
Carboxy terminus of the light chain
[C]
Amino terminus of the heavy chain
[D]
Carboxy terminus of the heavy chain
Answer: Carboxy terminus of the heavy chain
36
The immunoglobulin Joining chain (J-chain) is
[A]
only produced by T-Cells
[B]
only produced by neutrophils
[C]
associated with only multimeric forms of lgM and IgA
[D]
associated with IgE for histamine release
Answer: associated with only multimeric forms of lgM and IgA
37
All of the following are true EXCEPT
[A]
An epitope is a small portion of a macromolecule
[B]
the variable region domains contain the antigen recognition site
[C]
an antigenic determinant is a paratope
[D]
The class of an immunoglobulin is determined by its heavy chain
Answer: an antigenic determinant is a paratope
38
When a B-cell undergoes immunoglobulin class switching
[A]
the variable region of the light chain changes, but its constant region remains the sam
[B]
the variable region of the light chain remains the same, but its constant region changes
[C]
the variable region of the heavy chain remains the same but its constant region changes
[D]
both the variable and constant regions change
Answer: the variable region of the heavy chain remains the same but its constant region changes
39
The class of an immunoglobulin
[A]
is determined by Class I and Class II major histocompatibility complex proteins
[B]
is determined by the carbohydrate attached to the light chain is
[C]
determined by the antigen
[D]
is determined by the heavy chain type
Answer: is determined by the heavy chain type
40
The immunoglobulin class which is the least abundant in the normal adult is
[A]
IgG
[B]
IgA
[C]
IgM
[D]
IgE
Please share this page