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Bioinformatics Quiz | Bioinformatics Objective Type Questions and Answers

(21) ‘Laboratory work using computers and associated web based analysis generally online’ is referred as
[A] dry lab
[B] web lab
[C] wet lab
[D] insilico
Answer: web lab
(22) ‘Laboratory work using computers and computer generated models generally offline’ is referred as
[A] dry lab
[B] web lab
[C] wet lab
[D] insilico
Answer: dry lab

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(23) ‘Laboratory work using chemicals, drugs etc using water’ is referred as
[A] dry lab
[B] web lab
[C] wet lab
[D] insilico
Answer: wet lab
(24) The term used to refer something ‘performed on computer or computer simulation”
[A] dry lab
[B] web lab
[C] invitro
[D] insilico
Answer: insilico
(25) The first published completed gene sequence was of
[A] M 13 phage
[B] T 4 phage
[C] f X174
[D] lambda phage
Answer: f X174
(26) Step wise method for solving problems in computer science is called
[A] flowchart
[B] sequential design
[C] procedure
[D] algorithm
Answer: algorithm
(27) Margaret Dayhoff developed the first protein sequence database called
[A] SWISS PROT
[B] PDB
[C] Atlas of protein sequence and structure
[D] Protein sequence databank
Answer: Atlas of protein sequence and structure
(28) The term bioinformatics was coined by
[A] J D Watson
[B] Margaret Dayhoff
[C] Pauline Hogeweg
[D] Frederic Sanger
Answer: Pauline Hogeweg
(29) PRINTS are software used for
[A] detection of genes from genome sequence
[B] detection of tRNA genes
[C] prediction of function of a new gene
[D] Identification of functional domains/motifs of proteins
Answer: Identification of functional domains/motifs of proteins
(30) Phylogenetic relationship can be shown by
[A] Dendrogram
[B] Gene Bank
[C] Data retrieving tool
[D] Data search tool
Answer: Dendrogram
31 BLOSUM matrices are used for
[A] Multiple sequence alignment
[B] Pair wise sequence alignment
[C] Phylogenetic analysis
[D] All of the above
Answer: Pair wise sequence alignment
32 SWISS PORT is related to
[A] Portable data
[B] Swiss Bank data
[C] Sequence data bank
[D] Sequence sequence data
Answer: Sequence data bank
33 BLAST programme is used in
[A] DNA sequencing
[B] Amino acid sequencing
[C] DNA bar coding
[D] Bioinformatics
Answer: Bioinformatics
34 A data base of current sequence map of the human genome is called
[A] OMIM
[B] HGMD
[C] Golden path
[D] GeneCards
Answer: Golden path
35 Operating system is
[A] A collection of hardware components
[B] A collection of input-output devices
[C] A collection of software routines
[D] All of the above
Answer: A collection of software routines
36 Which of the following is a nucleotide sequence data base?
[A] EMBL
[B] SWISS PROT
[C] PROSITE
[D] TREMBL
Answer: EMBL
37 A single piece of information in a database is called
[A] File
[B] Field
[C] Record
[D] Data set
Answer: Field
38 Many scientists are very interested in studying mitochondrial DNA because it
[A] is only present in vertebrates closely related to humans.
[B] replicates by synthesizing an mRNA that then acts as a DNA polymerase.
[C] contains over 50% of the genes in the human genome.
[D] mutates rapidly and allows us to study evolution over short time scales.
Answer: mutates rapidly and allows us to study evolution over short time scales.
39 Your TA tells you to go to the NCBI Human Genome page. What does she probably want you to do?
[A] Determine what genes are around ‘your’ protein’s gene on its chromosome.
[B] Identify a DNA sequence and see if it came from a human.
[C] Look up papers about diseases caused by abnormalities in a certain protein.
[D] Look at colorful, rotating, 3-D pictures of the tertiary structure of a protein.
Answer: Determine what genes are around ‘your’ protein’s gene on its chromosome.
40 You see that your lab partner is staring at a colorful Swiss-Prot page. He’s probably trying to
[A] translate a DNA segment into protein.
[B] find out structural and functional information about a protein he’s identified.
[C] determine how many harmful mutations have been reported in a certain gene.
[D] identify an amino acid sequence.
Answer: find out structural and functional information about a protein he’s identified.

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