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Biomolecules MCQs | Biomolecules Short Questions and Answers

(1) The backbone of DNA is
[A] hydrophilic
[B] hydrophobic
[C] nuetral
[D] Both hydrophilic and hydrophobic
Answer: hydrophilic
(2) Which is the most stable form of DNA under normal physiological conditions
[A] A-DNA
[B] B-DNA
[C] Z-DNA
[D] H-DNA
Answer: B-DNA
(3) As far as the absorbance of DNA at 260nm. Which of the following is correct?
[A] individual nucleotides>ss DNA>dsDNA
[B] dsDNA>ssDNA> individual nucleotides
[C] ssDNA>dsDNA> individual nucleotides
[D] absorbance remains same
Answer: individual nucleotides>ss DNA>dsDNA
(4) Which of the following statement is true?
[A] DNA is more stable than RNA in alkaline condition because of the presence of 3’OH
[B] DNA is more stable than RNA in alkaline condition because of the presence of 2’ H compared to RNAs 2’OH
[C] RNA is more stable than DNA in alkaline condition because of the presence of 2’ and 3’OH compared to DNAs 2’H and 3’OH
[D] Both are equally stable in alkaline condition
Answer: DNA is more stable than RNA in alkaline condition because of the presence of 2’ H compared to RNAs 2’OH
(5) Dehydration of DNA samples may induce the formation of
[A] A-DNA
[B] B-DNA
[C] Z-DNA
[D] H-DNA
Answer: A-DNA
(6) An increase in temperature of a DNA sample causes change in
[A] absorbance at 260nm
[B] viscosity
[C] phosphodiester linkage
[D] absorbance and viscosity
Answer: absorbance and viscosity
(7) RNA-DNA hybrids are
[A] more stable than DNA-DNA hybrid
[B] more stable than RNA-RNA hybrid
[C] less stable than RNA-RNA hybrid
[D] less stable than RNA-RNA hybrid and DNA-DNA hybrid
Answer: less stable than RNA-RNA hybrid and DNA-DNA hybrid
(8) An increase Tm (melting temperature) for a ds-DNA may be due to high content of
[A] A+G
[B] A+T
[C] C+G
[D] none of the above
Answer: C+G
(9) Thymine is present in
[A] prokaryotic mRNA
[B] mammalian mRNA
[C] ribosomal RNA
[D] tRNA
Answer: tRNA
(10) RNA is genetic material in
[A] some virusus and prokaryotes
[B] some viruses only
[C] some virusus, prokaryotes and some primitive eukaryotes
[D] none of the above
Answer: some virusus and prokaryotes
(11) DNA has
[A] autocatalytic function
[B] heterocatalytic function
[C] both autocatalytic and heterocatalytic function
[D] none of the above
Answer: both autocatalytic and heterocatalytic function
(12) A nucleoside is composed of
[A] a base+ a sugar
[B] a base+ a sugar+ phosphate
[C] a base+ a phosphate
[D] none of these
Answer: a base+ a sugar
(13) Genetic mutation occurs in
[A] Protein
[B] RNA
[C] DNA
[D] Nucleus
Answer: DNA
(14) DNA is present in
[A] nucleus only
[B] nucleus, mitochondria and ER
[C] nucleus, mitochondria and choloroplast
[D] nucleus, mitochondria and RER
Answer: nucleus, mitochondria and choloroplast
(15) DNA is the genetic material in
[A] viruses, prokaryote and eukaryote
[B] prokaryote and eukaryote
[C] only in eukaryotes
[D] in some viruses, prokaryotes and eukaryotes
Answer: in some viruses, prokaryotes and eukaryotes
(16) The two strands in a DNA double is joined by

[A] Co-valent bond
[B] Hydrogen bond
[C] ionic bond
[D] phosphodiester bond
Answer: Hydrogen bond
(17) Chromatin is composed of
[A] nucleic acids and protein
[B] nucleic acids only
[C] proteins only
[D] none of these
Answer: nucleic acids and protein
(18) The basic repeating units of a DNA molecule is
[A] nucleoside
[B] nucleotide
[C] histones
[D] aminoacids
Answer: nucleotide
(19) Adjacent nucleotides are joined by
[A] covalent bond
[B] phosphodiester bond
[C] ionic bond
[D] peptide bond
Answer: phosphodiester bond
(20) The length of one turn of DNA is
[A] 3.4 Ao
[B] 34 Ao
[C] 20 Ao
[D] 3.04 Ao
Answer: 34 Ao

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