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Gas Chromatography General Knowledge Quiz | Gas Chromatography General Knowledge Multiple Choice Questions(MCQs) & Answers

(1) What are the benefits of decreasing the column internal diameter?
[A] Increased sample capacity
[B] Increased resolution
[C] Reduced risk of column overloading
[D] All of the above
Answer: Increased resolution
(2) Helium is generally preferred as carrier gas over nitrogen and hydrogen because
[A] it is inert
[B] it has a lower viscosity
[C] it doubles up as a party gas for balloons and funny voices
[D] all of above
Answer: all of above

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(3) What does the selectivity factor describe?
[A] The proportional difference in widths of two chromatographic peaks
[B] The maximum number of different species which a column can separate simultaneously
[C] The relative separation achieved between two species
[D] None of the above
Answer: The relative separation achieved between two species
(4) Theoretical plates are used to
[A] estimate the efficiency of a column
[B] determine the thickness of the stationary phase
[C] measure the distribution of the analyte between mobile and stationary phases
[D] None of the above
Answer: estimate the efficiency of a column
(5) Split injection is carried out by
[A] splitting the sample into smaller portions to inject sequentially
[B] splitting the sample into smaller portions to inject at the same time through parallel ports
[C] splitting off some of the sample so that it does not enter the column
[D] none of the above
Answer: splitting off some of the sample so that it does not enter the column
(6) Headspace analysis is carried out in order to
[A] analyse volatile compounds from solid or liquid samples
[B] determine the psychological state of the tutor
[C] analyse the column contents ahead of the sample
[D] determine non-volatiles
Answer: analyse volatile compounds from solid or liquid samples
(7) Which of the following detectors give mass flow-dependent signals?
[A] Electron capture detector
[B] Field ionisation detector
[C] Thermal conductivity detector
[D] All of the above
Answer: Field ionisation detector
(8) retention gap is placed between the injector and the front of the column to
[A] retain contaminants and prevent them from reaching the column
[B] retain the sample and release it gradually to the column
[C] prevent backflush of the injected solution
[D] all of the above
Answer: retain contaminants and prevent them from reaching the column
(9) In column switching chromatography
[A] compounds trapped on one column are eluted to another column
[B] one column is removed and replaced by another
[C] the flow to the column is switched on and off repeatedly
[D] any of the above
Answer: compounds trapped on one column are eluted to another column
(10) Which of the statements is correct?
[A] Gas chromatography is used to analyse gases
[B] Gas chromatography is used to analyse solids
[C] Gas chromatography is used to analyse gases, solutions and solids
[D] All of the above
Answer: All of the above
(11) Derivatisation of a sample is carried out to
[A] reduce polarity of the analytes
[B] increase the detector response
[C] increase volatility of the analytes
[D] all of the above
Answer: all of the above
(12) Resolution is proportional to the
[A] number of theoretical plates in a column
[B] square root of the number of theoretical plates in a column
[C] square of the number of theoretical plates in a column
[D] cube root of the number of theoretical plates in a column
Answer: square root of the number of theoretical plates in a column
(13) What is the typical internal diameter of fused silica capillary columns?
[A] 0.2-0.3 mm
[B] 0.3-0.5mm
[C] 0.5-1.0 mm
[D] 1.0-2.0 mm
Answer: 0.2-0.3 mm
(14) What useful information can be found from a Van Deemter plot?
[A] The selectivity factor
[B] Optimum mobile phase flow rate
[C] Optimum column temperature
[D] Optimum column length
Answer: Optimum mobile phase flow rate
(15) Which of the following detectors give concentration-dependent signals?
[A] Electron-capture detector
[B] Thermal conductivity
[C] Infra-red detector
[D] All of these
Answer: All of these
(16) The GC trace obtained after an experiment is called a
[A] chromatograph
[B] chromatogram
[C] chromatophore
[D] graph
Answer: chromatogram
(17) Which of these effects result from slow injection of a large sample volume?
[A] Increased resolution
[B] Decreased resolution
[C] Non-linear detector response
[D] Constant resolution
Answer: Decreased resolution
(18) Which of the following is not used for detection in GC?
[A] Infrared spectroscopy
[B] NMR
[C] Flame ionisation
[D] Electrical conductivity
Answer: NMR
(19) Sample retention in the column is measured by
[A] retention time
[B] retention factor
[C] retention index
[D] all of these
Answer: all of these
(20) Column bleeding occurs when
[A] elution of the analyte is extended over time
[B] the column is cracked and stationary phase leaks out
[C] traces of the stationary phase are eluted
[D] the column breaks during installation and causes personal injury
Answer: traces of the stationary phase are eluted

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