Aminoglycoside antibiotics such as kanamycin, tobramycin, neomycin are known inhibitors of DNA synthesis

Q. Aminoglycoside antibiotics such as kanamycin, tobramycin, neomycin are known inhibitors of DNA synthesis. It contains a cyclitol ring linked to a five or six membered sugars by glycosidic bonds. These antibiotics are

A.            Positively charged compound that to DNA and intercalates it.

B.            Positively charged compound that binds to DNA polymerase activity.

C.            Negatively charged compound to DNA and denatures it.

D.            Negatively charged compound that binds to histones

Answer: Positively charged compound that to DNA and intercalates it.

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