Bacterial secreted proteins effective in inactivating coronavirus

Researchers have discovered two bacterial secreted proteins that can effectively inactivate a series of viruses, including the novel coronavirus, dengue, and the HIV.

Initially, the researchers identified a soil bacterium from the gut of Aedes aegymosquitoes.

The whole bacterial genome was sequenced to characterize the bacterium and the scientists identified two proteins that can effectively impair a series of viruses, including dengue virus, HIV, and the novel coronavirus.

The two proteins contain a lipase domain.

The study indicated that certain lipases present a potent antiviral activity.

Previous studies showed either lipoprotein lipase or hepatic triglyceride lipase can impair (Hepatitis C) virus infection.

This invention will lead to the development of broad-spectrum antiviral drugs that might reduce the clinical burden caused by emerging viral diseases.