Which of the following statement is true regarding an enzyme DNA polymerase that catalyzes the elongation of complementary DNA strand?

The DNA polymerase is a template-directed enzyme that synthesizes new complementary strand from a parent strand but it requires the existing short nucleotide sequence for its elongation. Which of the following enzyme is required for the synthesis of this primer?

DNA polymerase III holoenzyme possesses

DNA replication is bidirectional and anti-parallel. Which of the statement is FALSE regarding the DNA replication?

Q. As the two strands of the double helix are separated, the positive supercoiling interferes with the further unwinding of DNA. Which of the following enzyme makes a break in a strand of DNA to release the supercoiling and facilitate the replication to occur?

Which of the following enzyme has a unique ability to introduce positive and negative supercoiling of the DNA and it is the target for antibacterial agents such as ciprofloxacin/quinolones?

The short strand of ........ primer is required for the replication of DNA

Which of the followings are the characteristic feature of DNA replication?

In prokaryotes, DNA replication begins at a single site that is rich in AT nucleotide sequence, where two strands unwind and separate. This ATP dependent process catalyzed by a protein

The DNA replication occurs in a semi-conservative manner which means

Q. Aminoglycoside antibiotics such as kanamycin, tobramycin, neomycin are known inhibitors of DNA synthesis. It contains a cyclitol ring linked to a five or six membered sugars by glycosidic bonds. These antibiotics are

Q. The Chargaff rules state that the number of purines and pyrimidines are equal (A+G = T + C)in any double-stranded DNA molecules. Watson and Crick later solved the structure of DNA and nitrogen base pairings. Which of the following base pairing rule is true: