Scientists from the Institute of Nano Science & Technology (INST), Mohali, an autonomous institute of the Department of Science and Technology Government of India, have synthesized a novel inorganic-organic hybrid compound that can inhibit breast, lung, and liver cancer cells, opening up new possibilities for metallodrugs.
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Key-Points
The solid compound based on phosphomolybdate cluster, an inorganic salt of phosphomolybdic acid, belongs to the Polyoxometalates (POMs) family, which had earlier been identified to have antitumor potential.
The team of scientists led by Dr. Monika Singh and Dr. Deepika Sharma has chalked out the mechanism by which the compound kills the cancer cells.
The research has been published in the journal Dalton Transactions.
POMs are an evolving class of inorganic metal oxides, which over the last decades, established promising biological activities by the virtue of their great diversity in structures and properties.
In order to probe into the mechanism of how the cancer cells are attacked by the compound, the team synthesised it by hydrothermal method.
In the past few decades, POMs have evolved as a promising candidate for future metallodrugs for combating cancer.
The compound synthesized by the INST team could open new avenues for antitumor applications.
