Nanoparticle Designed for Better Treatment of Disease

Another treatment for diseases looks like a new hope. Researchers from the University of Massachusetts, Amherst, in the U.S., created a nanoparticle that manipulates the immune system and effectively fights cancer cells.

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The new concept, Protein–Antibody Conjugates or PACs, combines two different approaches to drug delivery.

One is biologics, where the idea is to target a defective protein in the system by delivering proteins to it. An example of this is the case of insulin treatment. If a person is short of insulin, which is a protein, they are given a shot of this to balance the system.

The other approach is to use antibodies for drug delivery. Antibodies are something the body produces to detect a foreign substance inside the body.

Protein–antibody conjugates or PACs, developed by the group, which have a protein attached to the antibody, can zero in on, say, pancreatic cancer cells.

This could have impact on incurable diseases, so-called undruggable ones like pancreatic cancer.