The degree of inhibition for non competitive inhibition of an enzyme catalyzed reaction?

Q. The degree of inhibition for non competitive inhibition of an enzyme catalyzed reaction?

A.            Increase with increase substrate concentration

B.            Reaches with increase in substrate concentration

C.            Reaches a maxima with increase in substrate concentration and then decreases

D.            Decreases with increase in substrate concentration

Answer: Reaches a maxima with increase in substrate concentration and then decreases