Q. The reaction in DNA replication catalyzed by DNA ligase is
A. Addition of new nucleotides to the leading strand
B. Addition of new nucleotide to the lagging strand
C. Formation of a phosphodiester bond between the 3’-OH of one Okazaki fragment and the 5’-phosphate of the next on the lagging strand
D. Base pairing of the template and the newly formed DNA strand
Answer: Formation of a phosphodiester bond between the 3’-OH of one Okazaki fragment and the 5’-phosphate of the next on the lagging strand