Home » Transformation of Chlamydomonas is most efficient in which method? Algae MCQs Transformation of Chlamydomonas is most efficient in which method? December 31, 2021 2 Views Q. Transformation of Chlamydomonas is most efficient in which method? Lithium acetate methodElectroporationProtoplast based methodBoth electroporation and protoplast based method Answer: Protoplast based method