Transplantation of tissues/organs fails often due to non-acceptance by the patient’s body. Which type of immune is responsible for such rejections?

Transplantation of tissues/organs fails often due to non-acceptance by the patient’s body. Which type of immune is responsible for such rejections?

Option 1 : Autoimmune response
Option 2 : Hormonal immune response
Option 3 : Cell-mediated immune response
Option 4 : Physiological immune response