Which of the following enzyme has a unique ability to introduce positive and negative supercoiling of the DNA and it is the target for antibacterial agents such as ciprofloxacin/quinolones?

Q. Which of the following enzyme has a unique ability to introduce positive and negative supercoiling of the DNA and it is the target for antibacterial agents such as ciprofloxacin/quinolones?

A.            DnaA protein

B.            DNA helicase

C.            DNA gyrase

D.            DNA polymerase

Answer: DNA gyrase