Which of the following statements regarding enzyme inhibition is correct?

Q. Which of the following statements regarding enzyme inhibition is correct?

1. Competitive inhibition is seen when a substrate competes with an enzyme for binding to an inhibitor protein
2. Non-competitive inhibitors often bind to the enzyme irreversibly
3. Competitive inhibition is seen when the substrate and the inhibitor compete for the active site on the enzyme
4. Non-competitive inhibition of an enzyme can be overcome by adding large amount of substrate

Answer: Competitive inhibition is seen when the substrate and the inhibitor compete for the active site on the enzyme