Antigen and Antibody MCQs | Antigen and Antibody Multiple Choice Questions & Answers

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Questions
1 VDRL test is an example of
A Tube test
B Ring test
C Slide test
D none of these

Answer: Slide test
2 Weil-Felix reaction is based on sharing of antigens between
A sheep RBCs and EB virus
B mycoplasma and human O group RBCs
C rickettsial antigens and antigens of certain strains of Proteus
D none of these

Answer: rickettsial antigens and antigens of certain strains of Proteus
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3 Agglutination reaction is more sensitive than precipitation for the detection of
A Antigens
B Antibodies
C Complement
D Antigen-Antibody Complexes

Answer: Antigens

Antigen and Antibody – Multiple Choice Questions with Answers | EBook

4 In which of the following case a large lattice is formed?
A Antibody is in excess
B Antigens and antibodies are in optimal proportion
C Antigen is in excess
D None of these

Answer: Antigens and antibodies are in optimal proportion
5 Ring test is used for
A C-reactive protein test
B Ascoli’s thermoprecipitation test
C typing of streptococci and pneumococci
D all of the above

Answer: all of the above
6 Precipitation reaction can be converted into agglutination reaction by coating soluble antigen onto
A bentonite particles
B RBCs
C latex particles
D all of these

Answer: all of these
7 Monoclonal antibody production requires
A mouse splenic lymphocytes
B mouse myeloma cells
C both (a) and (b)
D none of these

Answer: both (a) and (b)
8 Quellung reaction is used for typing of
A Klebsiella pneumoniae
B Streptococcus pneumoniae
C Both (a) and (b)
D None of these

Answer: Both (a) and (b)
9 Slide agglutination reaction is/are useful for the identification of the culture(s) of
A Shigella
B Vibrio cholerae
C Salmonella
D All of these

Answer: All of these
10 Amount of various immunoglobulin classes can be measured by
A double diffusion in one dimension
B single diffusion in two dimensions
C single diffusion in one dimension
D double diffusion in two dimensions

Answer: single diffusion in two dimensions
11 Synthesis of antibodies takes place by which of the following cells?
A Bone marrow cells
B T-cells
C B-cells
D Lymph

Answer: B-cells
12 The basic structure of antibodies are______
A Y-shaped
B X-shaped
C Linear
D Hyperbolic

Answer: Y-shaped
13 What is the name of the hypervariable region of immunoglobin, which is responsible for its diversity?
A CDR
B Hinge region
C Epitope
D Agretope

Answer: CDR
14 Name the class of immunoglobulin which has a pentameric structure?
A IgE
B IgG
C IgA
D IgM

Answer: IgM
15 One principal function of the Class I and Class II major histocompatibility complex S proteins is to
A transduce the signal to the T-cell interior following antigen binding
B mediate immunoglobulin class switching
C present antigen for recognition by the T-cell antigen receptor
D stimulate production of interleukins

Answer: present antigen for recognition by the T-cell antigen receptor
16 Which immunoglobulin is the principal one found in secretions such as milk?
A IgG
B IgM
C IgA
D IgD

Answer: IgA
17 Who discovered the structure of immunoglobulin by treating it with beta-mercaptoethanol?
A Nisonoff
B Edelman
C Porter
D Whittekar

Answer: Edelman
18 Which of the following amino acid is found in the hinge region?
A Alanine
B Aspargine
C Proline and cysteine
D Phenylalanine

Answer: Proline and cysteine
19 Which immunoglobulin can pass through placenta?
A IgD
B IgE
C IgM
D IgG

Answer: IgG
20 Which of these immunoglobulins is present in external secretion?
A IgG
B IgM
C IgA
D IgE

Answer: IgA
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