Antigen and Antibody Quiz | Antigen and Antibody Objective Type Questions & Answers

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Questions
21 Name the class of immunoglobulin which takes part in hypersensitivity reaction?
A IgG
B IgE
C IgA
D IgM

Answer: IgE
22 Fluorescent treponemal antibody test is an example of
A indirect immunofluorescence
B direct immunofluorescence
C both (a) and (b)
D none of these

Answer: indirect immunofluorescence
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23 Counter-immunoelectrophoresis is used for the detection of
A Meningococcal antigen
B Hepatitis B surface antigen
C Alpha-fetoprotein
D All of these

Answer: All of these

Antigen and Antibody – Multiple Choice Questions with Answers | EBook

24 Commercially available ELISA kits are used for the detection of
A rotavirus
B hepatitis B surface antigen
C anti-HIV antibodies
D all of these

Answer: all of these
25 Precipitation reaction is relatively less sensitive for the detection of
A antigens
B antigen-antibody complexes
C antibodies
D complement

Answer: antibodies
26 All of the following are true of antigen EXCEPT which one of the following?
A They contain epitopes
B They will react with antibodies
C They contain antigenic determinants
D They contain paratopes

Answer: They contain paratopes
27 All of the following are true about antibodies, EXCEPT which one?
A They fix complement
B They occur on the surface of B-lymphocyte
C They predominate the primary immune response to antigen
D They are molecule with a single, defined amino acid sequence

Answer: They are molecule with a single, defined amino acid sequence
28 Which of the following statements best characterizes an antibody?
A An antibody contains high molecular weight RNA as its basic structure
B An antibody is composed of protein and cannot be distinguished from the albumin fraction of the serum proteins
C An antibody is composed of four identical protein subunits which may be caused to dissociate by treatment with urea
D An antibody contains protein as its major chemical component and its synthesis may be elicited by the administration of a foreign protein or polysaccharide

Answer: An antibody contains protein as its major chemical component and its synthesis may be elicited by the administration of a foreign protein or polysaccharide
29 Individuals unable to make the J protein found in certain immunoglobulins would be expected to have frequent infections of the
A brain
B blood
C liver
D intestinal tract

Answer: All of these
30 All of the following are true with respect to IgM antibodies EXCEPT which one
A they fix complement
B they occur on the surface of lymphocytes
C they predominate in the primary response to antigen
D they mediate allergic reaction

Answer: they mediate allergic reaction
31 One principal function of complement is to
A inactivate perforins
B mediate the release of histamine
C Bind antibodies attached to cell surfaces and to lyse these cells
D phagocytize antigens

Answer: Bind antibodies attached to cell surfaces and to lyse these cells
32 The major role of the complement system is to work in conjunction with
A antibodies to lyse cells via the C8 and C9 components
B the major histocompatibility complex for cell recognition
C antibodies to opsonize cells
D the T-cell receptor for production of lymphokines

Answer: antibodies to lyse cells via the C8 and C9 components
33 T-cell antigen receptors are distinguished from antibodies by which of the following
A T-Cell receptors are glycosylated
B T-cell receptors must interact with antigen uniquely presented by other cells but not with free antigen
C T-Cell receptors bind various cytokines
D T-Cell receptors bind complement to lyse cells

Answer: T-cell receptors must interact with antigen uniquely presented by other cells but not with free antigen
34 T-cell receptors or antibodies react with antigens
A because both are made by lymphocytes
B because of complementary of molecular fit of both with antigen
C because both 'have light chain and heavy chain polypeptides
D cause histamine release

Answer: because of complementary of molecular fit of both with antigen
35 The major immunoglobulin family to which a particular immunoglobulin belongs can be determined by sequential analysis of the 110 amino acids beginning from the
A Amino terminus of the light chain
B Carboxy terminus of the light chain
C Amino terminus of the heavy chain
D Carboxy terminus of the heavy chain

Answer: Carboxy terminus of the heavy chain
36 The immunoglobulin Joining chain (J-chain) is
A only produced by T-Cells
B only produced by neutrophils
C associated with only multimeric forms of lgM and IgA
D associated with IgE for histamine release

Answer: associated with only multimeric forms of lgM and IgA
37 All of the following are true EXCEPT
A An epitope is a small portion of a macromolecule
B the variable region domains contain the antigen recognition site
C an antigenic determinant is a paratope
D The class of an immunoglobulin is determined by its heavy chain

Answer: an antigenic determinant is a paratope
38 When a B-cell undergoes immunoglobulin class switching
A the variable region of the light chain changes, but its constant region remains the sam
B the variable region of the light chain remains the same, but its constant region changes
C the variable region of the heavy chain remains the same but its constant region changes
D both the variable and constant regions change

Answer: the variable region of the heavy chain remains the same but its constant region changes
39 The class of an immunoglobulin
A is determined by Class I and Class II major histocompatibility complex proteins
B is determined by the carbohydrate attached to the light chain is
C determined by the antigen
D is determined by the heavy chain type

Answer: is determined by the heavy chain type
40 The immunoglobulin class which is the least abundant in the normal adult is
A IgG
B IgA
C IgM
D IgE

Answer: IgA

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