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Hematology Quiz | Hematology Objective Type Questions and Answers

(21) The most common type of protein found in the cell membrane is:
[A] Lipoprotein
[B] Mucoprotein
[C] Glycoprotein
[D] Nucleoprotein
Answer: Glycoprotein
(22) The enzyme deficiency in the Embden-Meyerhof pathway that is responsible for most cases of nonspherocytic hemolytic anemia is:
[A] Hexokinase
[B] Phosphotriptokinase
[C] Pyruvate Kinase
[D] Glyceraldehyde 3-Phosphate
Answer: Pyruvate Kinase

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(23) Which of the following would correlate with an elevated ESR value?
[A] Osteoarthritis
[B] Polycythemia
[C] Decreased globulins
[D] Inflammation
Answer: Inflammation
(24) The most important practice in preventing the spread of disease is:
[A] Wearing masks during patient contact
[B] Proper handwashing
[C] Wearing disposable lab coats
[D] Identifying specimens from known or suspected HIV and HBV patients with a red label
Answer: Proper handwashing
(25) Iron is incorporated into the heme molecule in which of the following forms:
[A] Ferro
[B] Ferrous
[C] Ferric
[D] Apoferritin
Answer: Ferrous
(26) The most frequent cause of needle punctures is:
[A] Patient movement during venipuncture
[B] Improper disposal of phlebotomy equipment
[C] Inattention during removal of needle after venipuncture
[D] Failure to attach needle firmly to tube holder
Answer: Improper disposal of phlebotomy equipment
(27) What is the distribution of normal Hb in adults?
[A] 80-90% Hb A, 5-10% Hb A2, 1-5% Hb F
[B] >95% Hb A, <3.5 % Hb A2, <1-2% Hb F
[C] All of these
[D] None of these
Answer: >95% Hb A, <3.5 % Hb A2, <1-2% Hb F
(28) The maximum number of erythrocytes generated by one Multipotential Stem Cell is:
[A] 8
[B] 1
[C] 12
[D] 16
Answer: 16
(29) How are the globin chains genes arranged? Note: a means alpha, B means beta
[A] With a genes and B genes on the same chromosome including two a genes and two B genes
[B] With a genes and B genes on seperate chromosomes, two a genes on one chromosome and one B gene on a different chromosome
[C] With a genes and B genes on the same chromosome - including four a genes and four B genes
[D] With a genes and B genes on separate chromosomes - four a genes on one chromosome and two B genes on a different chromosome
Answer: With a genes and B genes on seperate chromosomes, two a genes on one chromosome and one B gene on a different chromosome
(30) Which of the following gathers, organizes, and directs light through the specimen?
[A] Ocular
[B] Objective lens
[C] Condenser
[D] Optical Tube
Answer: Condenser
31 In the bone marrow, RBC precursors are located:
[A] In the center of the hematopoietic cords
[B] Adjacent to megakaryocytes along the adventitial cell lining
[C] Surrounding fat cells in apoptotic islands
[D] Surrounding macrophages near the sinus membrane
Answer: Surrounding macrophages near the sinus membrane
32 During midfetal life, the primary source of blood cells is the:
[A] Bone marrow
[B] Spleen
[C] Lymph Nodes
[D] Liver
Answer: Liver
33 The layer of the erythrocyte membrane that is largely responsible for the shape, structure, and deformability of the cell is the:
[A] Integral protein
[B] Exterior lipid
[C] Peripheral protein
[D] Interior lipid
Answer: Peripheral protein
34 The acceptable range for hemoglobin values on a control sample is 13 + or - 0.4 g/dL. A hemoglobin determination is performed five times in succession on the same control sample. The results are (in g/dL. 12 12.3, 12, 12.2, and 12.1) These results are:
[A] Precise, but not accurate
[B] Both accurate and precise
[C] Accurate, but not precise
[D] Neither accurate nor precise
Answer: Precise, but not accurate
35 Which of the following cells may develop in sites other than the bone marrow?
[A] Monocyte
[B] Lymphocyte
[C] Megakaryocyte
[D] Neutrophil
Answer: Lymphocyte
36 A multilineage cytokine among the ILs is:
[A] IL-1
[B] IL-2
[C] IL-3
[D] IL-4
Answer: IL-1
37 In the Iron cycle, the transferrin receptor carries:
[A] Iron out of duodenal cells from the intestinal lumen
[B] Iron out of duodenal cells into the plasma
[C] transferrin-bound iron in the plasma
[D] transferrin-bound iron into erythrocytes
Answer: transferrin-bound iron into erythrocytes
38 Which single feature of normal RBC's is most responsible for limiting their life span?
[A] Loss of mitochondria
[B] Increased flexibility of the cell membrane
[C] Reduction of Hb iron
[D] Loss of nucleus
Answer: Loss of nucleus
39 The hexose monophosphate pathway activity increases the RBC source of
[A] Glucose and lactic acid
[B] 2,3-BPG and methemoglobin
[C] NADPH and reduced glutathione
[D] ATP and other purine metabolites
Answer: NADPH and reduced glutathione
40 The lipids of the RBC membrane are arranged:
[A] In chains beneath a protein exoskeleton
[B] So that the hydrophobic portions are facing the plasma
[C] In a hexagonal lattice
[D] In two layers that are not symmetric in composition
Answer: In two layers that are not symmetric in composition

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