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Principles and Processes of Biotechnology MCQs | Principles and Processes of Biotechnology Multiple Choice Questions and Answers

(1) A singe strand of nucleic acid tagged with a radioactive molecules is called
[A] Vector
[B] Selectable marker
[C] Plasmid
[D] Probe
Answer: Probe
(2) Which one of the following is a case of wrong matching ?
[A] Somatic Hybridization- Fusion of two diverse cells
[B] Vector DNA- Site for tRNA synthesis
[C] Micropropagation- in vitro production of plants in large numbers
[D] Callus- Unorganised mass of cells produced in tissue culture
Answer: Vector DNA- Site for tRNA synthesis
(3) Which one is a true statement regarding DNA polymerase used in PCR ?
[A] It is used to ligate introduced DNA in recipients cells
[B] It serves as a selectable marker
[C] It is isolated from a virus
[D] It remains active at high temperature
Answer: It remains active at high temperature
(4) For transformation, micro-particles coated with DNA to be bombarded with gene gun are made up of
[A] Silver or platinum
[B] Platinum or zinc
[C] Silicon or platinum
[D] Gold or trungsten
Answer: Gold or trungsten
(5) Biolistics (gene-gun) is suitable
[A] Disarming pathogen vector
[B] Transformation of plant cells
[C] Constructing recombinant DNA by joining with vectors
[D] DNA fingerprinting
Answer: Transformation of plant cells
(6) In genetic engineering, the antibiotics are used
[A] As selectable markers
[B] To select healthy vectors
[C] As sequence from where replication starts
[D] To keep the culture free of infection
Answer: As selectable markers
(7) Which one of the following represents a palindromic sequence in DNA ?
[A] 5’-GAATTC-3 3’-CTTAAG-5’
[B] 5’-CCAATG-3’
[C] 3’-GAATCC-5’
[D] 5’-CATTAG-3’ 3’-GATAAC-5’
Answer: 5’-GAATTC-3 3’-CTTAAG-5’
(8) The colonies of recombinant bacteria appear white in contrast to blue colonies of non- recombinant bacteria because of
[A] Insertional inactivation of alpha galactosidese in recombinant bacteria
[B] Inactivation of glycosides enzyme in recombinant bacteria
[C] Non-recombinant bacteria containing beta galactosidase
[D] Insertional inactivation of alpha galactosidase
Answer: Non-recombinant bacteria containing beta galactosidase
(9) Which of the following is not correctly matched for the organism and its cell wall degrading enzyme ?
[A] Algae - Methylase
[B] Fungi - Chitinase
[C] Bacteria - Lysozyme
[D] Plant cells – Cellulase
Answer: Algae - Methylase
(10) DNA fragments generated by the restriction endonucleases in a chemical reaction can be separated by
[A] Electrophoresis
[B] Restriction mapping
[C] Centrifugation
[D] Polymerase chain reaction
Answer: Electrophoresis
(11) An analysis of chromosomal DNA using the southern hybridization technique does not use
[A] Electrophoresis
[B] Blotting
[C] Autoradiography
[D] PCR
Answer: PCR
(12) In vitro clonal propagation in plants is characterized by
[A] PCR and RAPD
[B] Northern blotting
[C] Electrophoresis and HPLC
[D] Microscopy
Answer: PCR and RAPD
(13) Which vector can be clone only a small fragment of DNA ?
[A] Bacterial artificial chromosome
[B] Yeast artificial chromosome
[C] Plasmid
[D] Cosmid
Answer: Plasmid
(14) Commonly used vectors for human genome sequencing are
[A] T- DNA
[B] BAC and YAC
[C] Expression vectors
[D] T/A cloning vectors
Answer: BAC and YAC
(15) Which of the following is a plasmid ?
[A] pBR322
[B] BamH-I
[C] Hind-III
[D] EcoRI
Answer: pBR322
(16) Restriction endonucleases are must widely used in recombinant DNA technology. They are obtained from
[A] Bacteriophages
[B] Bacterial cells
[C] Plasmids
[D] All Prokaryotie Cells
Answer: Bacterial cells
(17) Viral genome incorporated into host DNA is called
[A] Prophase
[B] Prophage
[C] Bacteriophage
[D] None of these
Answer: Prophage
(18) Two microbes found to be very useful in genetic engineering are
[A] Crown gall bacterium and Conorhabditis elegens
[B] Escherichia coli to Agrobacterium tumifaciens
[C] Vibria choleraeand a tailed bacteriphage
[D] Dipococens species and psendomonasap
Answer: Escherichia coli to Agrobacterium tumifaciens
(19) Who disconnected recombinant DNA technoledge ?
[A] Har Gobind Khorana
[B] James Watson & Francis Crick
[C] Stanly Cohen & Herbert Boyer
[D] Watter Sutton
Answer: Stanly Cohen & Herbert Boyer
(20) Find out the wrong statement ?
[A] Mobile genetic element, Transposons were visualized by Barbara Mc Clintock
[B] Udder cell a somatic cell is used to produce the cloned sheep by nuclear transplantation method
[C] Dr. Ian Wilmut produced a cloned sheep called Dolley
[D] DNA ligases are used to cleave a DNA molecule
Answer: DNA ligases are used to cleave a DNA molecule

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