Biopharmaceuticals - Questions and Answers for Competitive Exams | GkSeries

49. Randomization is done in _____

• [A] Phase I trial.
• [B] Phase II trial.
• [C] Phase III trial.
• [D] Phase IV trial.

Answer: Option [C]

50. In phase II trial, the drug is tested on _______ volunteers.

• [A] 50 - 300.
• [B] 300 -600.
• [C] 600 -900.
• [D] 600 -900.

Answer: Option [A]

51. Which of the cell lines are widely used for drug screening?

• [A] Immortalized cell lines
• [B] Primary cell lines
• [C] Cancer cell lines
• [D] All the above

Answer: Option [A]

52. 6-mercaptopurine is used in the treatment of childhood _______.

• [A] lymphoma
• [B] leukemia
• [C] sarcoma
• [D] thrombocytopenia

Answer: Option [B]

53. The purine released by PNP activity is used in the synthesis of _______.

• [A] proteins
• [B] DNA
• [C] lipids
• [D] carbohydrates

Answer: Option [B]

54. Isoprenoids is otherwise called as _______.

• [A] steroids
• [B] terpenoids
• [C] alkaloids
• [D] falvanoids

Answer: Option [B]

55. The precursor for the synthesis of flavanoids is _______.

• [A] coumaryl CoA.
• [B] chalcone
• [C] malonyl CoA.
• [D] mevalonate

Answer: Option [B]

56. The alkylation can be done in _______.

• [A] cysteine
• [B] lysine
• [C] histidine
• [D] all the above.

Answer: Option [D]

57. Genotyping is done to determine the genotype of an individual by examining the _______.

• [A] RNA sequence.
• [B] DNA sequence.
• [C] protein sequence.
• [D] carbohydrate

Answer: Option [B]

58. Cancer is caused due to _______.

• [A] hereditary
• [B] mutation
• [C] virus
• [D] all the above.

Answer: Option [D]

59. The host cell used for the production of erythropoietin is _______.

• [A] E. coli.
• [B] Yeast
• [C] CHO cell lines.
• [D] BHK cell lines.

Answer: Option [C]

60. IFNs produced using CHO cell lines include _______.

• [A] Betaferon
• [B] Avonex
• [C] Betaseron
• [D] Epogen

Answer: Option [B]