Neurology Quiz | Neurology Objective Type Questions and Answers

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Questions
21 A 34 year old male presents with back-pain and weakness. Which of the following would support a diagnosis of prolapsed intervertebral disc?
A bilateral symmetrical nerve involvement
B Loss of sensation over the left outer upper thigh
C no evidence of nerve compression
D pain which is worse on resting

Answer: Loss of sensation over the left outer upper thigh
22 Which of the following is true of human neurons?
A myelin sheaths extend across the nodes of Ranvier.
B unmyelinated fibres have faster conduction.
C sodium ion influx occurs during the action potential.
D the action potential increases with increased stimulation.

Answer: sodium ion influx occurs during the action potential.
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23 A 24 year old female presents with vague frontal headaches and visual disturbance. She has a past history of acne for which she is receiving treatment. Examination reveals her to be obese with a blood pressure of 110/70 mmHg. There is absence of the central retinal vein pulsation on fundoscopic examination. Which of the following drugs account for these findings?
A Isotretinoin
B Ampicillin
C Topical tetracycline
D Dianette

Answer: Dianette
24 A 15 year old boy presents with tremor of both hands. Over the previous months he has eveloped a mild dysarthria. He has a history of behavioural problems, of a depressive/psychotic nature. The most likely diagnosis is:
A Alzheimer's disease
B Huntington's disease
C Neuroacanthocytosis
D Wilson's disease

Answer: Wilson's disease
25 A 48-year-old female patient develops an acute, severe and isolated right C6 radiculopathy affecting both the motor and sensory roots. She is examined in an EMG clinic 3 weeks after the onset of symptoms. Which of the following statements is true?
A Absent sensory nerve potentials would be expected on examination of the thumb and index finger on the right.
B A repeat examination 12 months later is likely to reveal rapidly recruited low amplitude short duration motor units in the clinically involved muscle on EMG.
C Fibrillation potentials would be expected in the right brachioradialis and abductor pollicus brevis.
D Triceps tendon jerk is likely to be depressed or absent.

Answer: Absent sensory nerve potentials would be expected on examination of the thumb and index finger on the right.
26 A 25-year-old woman presents with a severe migraine. Which of the following is not a recognised feature of migraine?
A Some symptoms improved by tricyclic antidepressants
B Third nerve palsy
C External opthalmoplegia
D bilateral fortification spectra

Answer: External opthalmoplegia
27 Which of the following is a characteristic feature of transient global amnesia?
A abnormal behaviour
B confabulation
C apraxia
D normal perception

Answer: normal perception
28 A 20-year-old female presents with acute onset of left foot drop. Examination reveals weakness of ankle dorsiflexion and eversion. There is a small area of sensory loss in the first web space. Reflexes were all present and plantars flexor. Which of the following nerves is likely to be involved?
A Tibial nerve
B Common peroneal nerve
C Sciatic nerve
D Femoral nerve

Answer: Common peroneal nerve
29 Which ONE of the following would be expected in a third nerve palsy?
A Enophthalmos
B Constricted pupil
C Convergent strabismus
D Unreactive pupil to light

Answer: Unreactive pupil to light
30 Causes of dilated pupils include:
A Argyll Robertson pupil
B Ethylene glycol poisoning
C Myotonic dystrophy
D Organophosphate poisoning

Answer: Ethylene glycol poisoning
31 A demyelinating polyneuropathy is typically caused by:
A Diabetes
B Excessive alcohol
C Hereditary motor-sensory neuropathy
D Renal failure

Answer: Hereditary motor-sensory neuropathy
32 Which of the following associations is correct?
A Renal transplantation and Non-Hodgkin's lymphoma
B Hepatitis B and aplastic anaemia
C Turner's syndrome and acute myeloid leukaemia
D Basophilia and chronic myeloid leukaemia

Answer: Hepatitis B and aplastic anaemia
33 Regarding pseudotumours cerebri (benign hypercranial hypertension) which is true?
A A mildly increased CSF cell count is typical.
B May be caused by prolonged steriod therapy.
C Is occasionally associated with focal neurological signs.
D Frequently presents with ataxia.

Answer: May be caused by prolonged steriod therapy.
34 A complete unilateral facial hemiparesis may be caused by which of the following?
A An intracranial tumour
B Birth injury
C Cerebellar atrophy
D Myasthenia gravis

Answer: Birth injury
35 A 65-year-old man presents with 4 months history of swallowing difficulties (worse with liquids than solids). He also complains of nasal regurgitation, coughing and choking episodes during meals and slight dysarthria. He lost 1 stone over the last 8 weeks. Which of the following investigations is the most appropriate for this case?
A Gastroscopy
B Barium swallow
C CXR
D Acetyl choline receptors antibodies

Answer: Acetyl choline receptors antibodies
36 A 60-year-old man presents with an episode of memory loss. Three days earlier he had become confused. His wife led him into the house - he apparently sat down at her request, and had a cup of tea. He then wandered around the house, confused, but remained conscious and able to have some conversation with his wife, though continuing to ask similar questions repeatedly. After three hours, he abruptly returned to normal and had no recollection of the events. What is the most likely diagnosis?
A alcohol related amnesia
B chronic subdural haematoma
C complex partial status epilepticus
D transient global amnesia

Answer: transient global amnesia
37 A 40-year-old man has had decreased mentation with confusion as well as increasing incoordination and loss of movement in his right arm over the past 6 weeks. An MRI scan shows 0.5 to 1.5 cm lesions in cerebral hemispheres in white matter and at the grey-white junction that suggest demyelination. A stereotatic biopsy is performed, and immunohistochemical staining of the tissue reveals JC papovavirus in oligodendrocytes. Which of the following laboratory test findings is most likely to be associated with these findings?
A CD4 lymphocyte count of 90/microliter
B Haemoglobin A1c of 9.8%
C HDL cholesterol of 0.7 mmol/L
D Oligoclonal bands in CSF

Answer: CD4 lymphocyte count of 90/microliter
38 A 21 year old female with epilepsy is well controlled on sodium valproate 600mg bd and had been taking oral contraceptives for three years. She presented to her general practitioner 12 weeks pregnant. Which of the following is correct?
A An alternative anticonvulsant should be used in place of sodium valproate
B Interaction of sodium valproate with the oral contraceptive increased the risk of pregnancy
C The dose of sodium valproate should be increased
D There is an increased risk of a neural tube defect in her fetus

Answer: There is an increased risk of a neural tube defect in her fetus
39 A 68-year-old man presents with progressive visual impairment. On examination there is an incongruous homonymous hemianopia. The most likely anatomical site of the neurological lesion is at:
A optic nerve
B optic tract
C chiasma
D optic radiation

Answer: optic tract
40 Which of the following is true of tetanus?
A failure to culture Clostridium tetani from the wound would make the diagnosis doubtful
B infection confers lifelong immunity
C there is a characteristic EEG
D cephalic tetanus causes severe dysphagia

Answer: cephalic tetanus causes severe dysphagia

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