Neurology Quiz | Neurology Short Questions and Answers

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Questions
41 A 25-year-old female presents with 2 days history of diplopia and unsteadiness. 2 weeks ago she suffered an upper respiratory tract infection. On examination there is complete opthalmoplegia, areflexia and gait ataxia. Which of the following blood tests is the most likely to confirm the underlying diagnosis?
A Acetylcholine receptors antibodies
B Anti GM1 antibodies
C Anti GQib antibodies
D Anti Hu antibodies

Answer: Anti GQib antibodies
42 A 70-year-old man presents with weight loss, lower limb weakness and dry mouth. He has been a heavy smoker. On examination, he looks cachectic; he has proximal lower limb weakness, areflexia (reflexes normalise with repetitive muscle contraction). There is no wasting or fasciculations. Sensory examination is normal. Which of the following blood test is the most likely to confirm the diagnosis?
A Acetylcholine receptors
B Voltage gated calcium channels antibodies
C Anti GM1 antibody
D Antinuclear antibody

Answer: Voltage gated calcium channels antibodies
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43 50-year-old old man is admitted to hospital unconsious, and smelling of alcohol. One hour after admission, he becomes suddenly sweaty with a regular tachycardia of 110 bpm and a BP of 100/50. What is the diagnosis?
A Alcohol withdrawal.
B Hepatic encephalopathy.
C Hypoglycaemia.
D Subdural haematoma.

Answer: Hypoglycaemia.
44 A 25-year-old old woman presents with 2 hrs of a unilateral temporal headache increasing in severity. The Pain is of a throbbing character and is exacerbated by light. There are no abnormal signs on examination. What is the diagnosis?
A Acute Subarachnoid haemorrhage.
B Cluster headache.
C Intracranial Tumour.
D Migraine.

Answer: Migraine.
45 A 35-year-old man has wrist drop of his right hand. Examination reveals a small area of sensory loss on the dorsum of the hand. Which of the following nerves is likely to be involved?
A Median nerve
B Ulnar nerve
C Long thoracic nerve
D Radial nerve

Answer: Radial nerve
46 Which of the following features are not compatible with the diagnosis of motor neuron disease?
A Dementia
B Dysphagia
C Muscle cramps
D Optic atrophy

Answer: Optic atrophy
47 A 63 year old male is admitted with acute onset unsteadiness of gait, dizziness and dysphagia. Examination revealed a right-sided Horner's syndrome, nystagmus, loss of pain and temperature sensation on the left side of the trunk and in the left arm and leg, and gait ataxia. What is the most likely diagnosis?
A leaking posterior communicating artery aneurysm
B left sided acoustic neuroma
C posterior inferior cerebellar artery occlusion
D right sided pontine infarct

Answer: posterior inferior cerebellar artery occlusion
48 A 25 year-old lady recently diagnosed with rheumatoid arthritis. She has developed weakness, double vision and tiredness. Examination reveals bilateral weakness of eye abduction, bilateral ptosis, slightly reduced proximal motor power in the limbs, normal reflexes and sensation. What is the diagnosis?
A Chronic progressive external opthalmoplegia.
B Guillain-Barre syndrome.
C Multiple sclerosis.
D Myasthenia gravis.

Answer: Myasthenia gravis.
49 In herpes simplex encephalitis which of the following statements is correct?
A brain MRI is characteristically normal
B temporal lobe involvement is common
C fits are uncommon
D cold sores or genital herpes are usually present

Answer: temporal lobe involvement is common
50 Which of the following clinical manifestations suggests Guillain Barré Syndrome?
A Weakness beginning in the arms
B Asymmetrical involvement of distal muscles
C Bulbar involvement in about 50% of cases
D Brisk tendon reflexes

Answer: Bulbar involvement in about 50% of cases
51 A 16 year old girl presented with a three week history of headache and horizontal diplopia on far right lateral gaze. On two separate occasions she noted dimmed vision whilst bending forwards. Over the last year she had gained 12 kilograms in weight. On examination, her weight was 95 kg, and height 162cms. Neurological examination revealed bilateral papilloedema and a partial right sixth cranial nerve palsy. What is the most likely diagnosis?
A Benign intracranial hypertension.
B Multiple sclerosis.
C Pituitary tumour
D Superior sagittal vein thrombosis.

Answer: Benign intracranial hypertension.
52 An 80-year-old woman has a three month history of progressive numbness and unsteadiness of her gait. On examination, there is a mild spastic paraparesis, with brisk knee reflexes, ankle reflexes are present with reinforcement, extensor plantars, sensory loss in the legs with a sensory level at T10, impaired joint position sense in the toes, and loss of vibration sense below the iliac crests. Investigations were as follows:- haemoglobin 12.0 g/dl MCV 99 fl What is the most likely diagnosis?
A anterior spinal artery occlusion
B dorsal meningioma
C multiple sclerosis
D subacute combined degeneration of the cord

Answer: dorsal meningioma
53 A 50 year-old male epileptic presents with paraesthesia of hands and feet. He also has unsteadiness when walking. On examination he has Dupytren's contracture in his left hand, a peripheral sensory neuropathy and palpable lymph nodes in his neck and axillae. Which of the following drugs is the most likely cause of these features?
A Carbamazepine.
B Clonazepam
C Lamotrigine.
D Phenytoin.

Answer: Phenytoin.
54 A 17-year-old man has been diagnosed with schizophrenia 4 weeks ago. He was started on haloperidol. Two weeks later he was found confused and drowsy. On examination he was pyrexial (40.7 C), rigid with blood pressure of 200/100. Which of the following treatment will you initiate?
A phenytoin
B diazepam
C cefuroxime
D dantrolene

Answer: dantrolene
55 A lesion of the occipital lobe causes:
A Acalculia
B Astereogenesis
C Constructional apraxia
D Cortical blindness

Answer: Cortical blindness
56 A 52 year old man has a slurring of his speech. Examination reveals bilateral partial ptosis and frontal balding, and difficulty releasing his grip after shaking hands. What is the most likely diagnosis?
A myasthenia gravis
B Eaton-Lambert syndrome
C Myotonia dystrophica
D Duchenne muscular dystrophy

Answer: Myotonia dystrophica
57 A young teenager presents with fever and headache. He has received oral Amoxycillin for 3 days. Which of the following CSF findings would exclude a partially treated meningitis?
A Negative gram stain
B A CSF glucose of 45% of blood glucose
C A white cell count of 50
D A negative CSF culture

Answer: A white cell count of 50
58 Which of the following would be expected following distal occlusion of the posterior cerebral artery?
A cerebellar ataxia
B contralateral hemiplegia
C dysarthria
D homonymous hemianopia

Answer: homonymous hemianopia
59 Which of the following associations of muscles and nerve supply are NOT true:
A Triceps and C7
B Deltoid and C5
C Gastroenemius and S1
D Long flexors of fingers and C6

Answer: Long flexors of fingers and C6
60 Which of the following relate to Dopa-decarboxylase inhibitors?
A enhance the effect of levodopa on the substantia nigra
B reduce the extracerebral complications of L-dopa therapy
C have anticholinergic activity
D should not be given in combination with dopamine agonists

Answer: reduce the extracerebral complications of L-dopa therapy

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