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Immunology Quiz | Immunology Multiple Choice Questions and Answers

(1) What main characteristic of HIV makes the virus difficult to treat with a single drug?
[A] Its ability to destroy drugs
[B] Impenetrable capsule
[C] Its ability to mutate
[D] Its environmental durability
Answer: Its ability to mutate
(2) What HIV protein helps insert the HIV provirus into the host's DNA?
[A] Transcriptase
[B] Integrase
[C] Protease
[D] Dismutase
Answer: Integrase

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(3) What is the term applied to white blood cells squeezing between endothelial cells lining the blood vessel to reach the site of an infection?
[A] Diapedesis
[B] Chemotaxis
[C] Phagocytosis
[D] Enucleation
Answer: Diapedesis
(4) What is an important mechanism white blood cells use to kill bacteria, fungi and other invading pathogens?
[A] Asphyxiation
[B] Oxidative activity
[C] Fright
[D] Drowning
Answer: Oxidative activity
(5) What product of the immune system attaches to bacteria, making them easier to eat by white blood cells?
[A] Hemoglobin
[B] Antibody
[C] Antigen
[D] Both A and B
Answer: Antibody
(6) What's a specific term for a bacterial or other foreign protein that initiates antibody production by the body?
[A] Peptide
[B] MHC II molecule
[C] Complement
[D] Antigen
Answer: Antigen
(7) Which of these produces and secretes antibodies in the body?
[A] Bacteria
[B] Plasma Cell
[C] Red blood cell
[D] Virus
Answer: Plasma Cell
(8) In HIV infection, reverse transcription describes which of the following?
[A] Converting viral DNA into RNA
[B] Converting viral RNA into DNA
[C] Converting proteins into viral RNA
[D] Both A and B
Answer: Converting viral RNA into DNA
(9) Name the process a cell such as a neutrophil or a macrophage uses to ingest (eat) its prey.
[A] Halitosis
[B] Chemotaxis
[C] Botulism
[D] Phagocytosis
Answer: Phagocytosis
(10) What host cell membrane structures enable the attachment of a virus like human immunodeficiency virus (HIV)?
[A] Ion channels
[B] Nuclear pores
[C] Ribosomes
[D] Receptors
Answer: Receptors
(11) A latent, measles-like viral infection &, presumably, a defect in cellular immunity is associated with which of the following diseases?
[A] Hereditary angioedema
[B] Systemic lupus erythematous (SLE)
[C] Subacute sclerosing panencephalitis (SSPE)
[D] DiGeorge syndrome
Answer: Subacute sclerosing panencephalitis (SSPE)
(12) Megakaryocytes are minimally immunoresponsive. What type of cell do megakaryocytes give rise to?
[A] RBC
[B] Platelets
[C] Leukocytes
[D] Monocytes
Answer: Platelets
(13) Rh disease & Goodpasture's syndrome are which type of hypersensitivity reaction?
[A] Type I
[B] Type II
[C] Type III
[D] Type IV
Answer: Type II
(14) Skin testing is useful in the diagnosis of which type of hypersensitivity reaction?
[A] Type I
[B] Type II and Type III
[C] Type IV
[D] Type I and IV
Answer: Type I and IV
(15) After playing in the bushes during a camping trip, a 7-year-old girl complains of intense itching & blistering of the hands, arms, & legs. What is the most likely condition & what type of hypersensitivity reaction is she displaying?
[A] Hives; Type I reaction
[B] Hives; Type IV reaction
[C] Contact Dermatitis; Type IV reaction
[D] Contact Dermatitis; Type I reaction
Answer: Contact Dermatitis; Type IV reaction
(16) Complement activation is a part of which type of hypersensitivity reaction?
[A] Type I
[B] Type II and Type III
[C] Type IV
[D] Type III and IV
Answer: Type II and Type III
(17) An 18-year-old teenager with a history of asthma as a young child, which she “outgrew” by the time she was in first grade, presents to her primary care physician in November 4 months pregnant, with wheezing and cough for the last month. On questioning, she admits to ragweed hayfever and frequent heartburn. On exam, she is coughing at frequent intervals. Chest is clear to auscultation with fair breath sounds throughout. There is slightly prolonged expiratory phase. What is the most appropriate treatment for this patient:
[A] Prn albuterol inhaler, loratadine and calcium carbonate antacid.
[B] Prn albuterol inhaler, beclomethasone inhaled corticosteroid and ranitidine.
[C] Prn albuterol inhaler, budesonide inhaled corticosteroid, ranitidine and oral steroid burst.
[D] Prn albuterol inhaler, oral steroid burst and proton pump inhibitor.
Answer: Prn albuterol inhaler, loratadine and calcium carbonate antacid.
(18) In treating allergic rhinitis, which of the following medication or medications control the symptoms of congestion, rhinorrhea and itching.
[A] Antihistamine
[B] Anticholinergic
[C] Decongestant
[D] Nasal corticosteroid
Answer: Nasal corticosteroid
(19) A 52-year-old male with known asthma for 27 years is seen in your office for a follow up of his asthma. He states his asthma has been in good control on his low dose of inhaled corticosteroid. But when asked about albuterol use, he says he uses it 2-3 times daily. When asked about nighttime awakening due to asthma, he states he awakes because of asthma 3 times per month. He also tells you his asthma has been in good control and that he has not missed a day of work. A PFT indicates he has an FEV1 of 81% predicted. You would characterize his asthma as:
[A] Mild intermittent
[B] Mild persistent
[C] Moderate persistent
[D] Severe persistent
Answer: Mild persistent
(20) A 10-year-old girl has had asthma for 18 months. She typically complains of asthma symptoms 3 times per week on the average, with daily symptoms when she has a URIs. She has never been hospitalized for asthma but has had 2 ED visits for wheezing with URIs. She complains of cough and shortness of breath with strenuous exercise. Her FEV1 and PEFR are both >80% predicted. Her treatment to date has been an albuterol inhaler prn. At this point, the one clearly inadequate therapy for this patient is:
[A] Start a leukotriene antagonist daily, albuterol inhaler prn and before exercise
[B] Start an inhaled corticosteroid at low to moderate dose, continue albuterol prn and before exercise
[C] Start the patient on a combined controller inhaler with inhaled steroid and long acting bronchodilator
[D] Start the patient on an inhaled steroid and leukotriene antagonist, and albuterol inhaler before exercise and prn
Answer: Start the patient on an inhaled steroid and leukotriene antagonist, and albuterol inhaler before exercise and prn

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