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Free download in PDF Immunology Short Questions and Answers for competitive exams. These short objective type questions with answers are very important for Board exams as well as competitive exams. These short solved questions or quizzes are provided by Gkseries.
41
Congenital absence of the late complement components (C5, C6, C7, C8) is most often associated with:
[A]
Viral infections
[B]
Recurrent Neisserial infections
[C]
Lupus-like disease
[D]
Candidiasis
Answer: Recurrent Neisserial infections
42
The most common cause of chronic urticaria, especially in adults, is:
[A]
Food allergy
[B]
Connective tissue disease
[C]
Drug allergy
[D]
Idiopathic
43
Which of the following types of infection are increased in patients with humoral or B-cell immune deficiencies?
[A]
Sinusitis
[B]
Otitis media
[C]
Pneumonia
[D]
All of the above
44
The major advantage of second generation antihistamines is:
[A]
They do cross the blood brain barrier and help patients to relax
[B]
They are very long acting
[C]
They cause decongestion as well as decreasing rhinorrhea
[D]
They minimally cross the blood brain barrier and have a decreased sedation effect
Answer: They minimally cross the blood brain barrier and have a decreased sedation effect
45
Reasonable recommendations for a patient with moderate persistent asthma poorly controlled on low dose inhaled corticosteroids include all except:
[A]
Add salmeterol inhaler BID
[B]
Double the dose of inhaled corticosteroid
[C]
Add a leukotriene modifier
[D]
Add nebulized cromolyn BID
Answer: Add nebulized cromolyn BID
46
Drug of choice for uncomplicated acute urticaria is:
[A]
Corticosteroid
[B]
Antihistamines (H2 type)
[C]
Antihistamines (H1 type)
[D]
Subcutaneous terbutaline
Answer: Antihistamines (H1 type)
47
All of the following medications can affect late phase (including by prophylaxis of the immediate allergic response) response in asthma except:
[A]
Corticosteroids
[B]
Leukotriene modifiers
[C]
Cromolyn sodium
[D]
Albuterol
48
As part of the work up of adult asthma, which of the following reproducible, pre and post bronchodilator pulmonary function test results would be interpreted as showing significant reversibility?
[A]
a 15% increase in FEF 25-75%
[B]
a 15% increase in FEV1 (425 ml improvement)
[C]
a 20% increase in FEV1 (180 ml improvement)
[D]
a 15% increase in FEV1/FVC ratio
Answer: a 15% increase in FEV1 (425 ml improvement)
49
Eczema in an infant most commonly occurs in/on the:
[A]
Antecubitutal and Popliteal fossae
[B]
Perineal region
[C]
Scalp and flexural areas
[D]
Extensor surface of arm and legs
Answer: Scalp and flexural areas
50
Indications for immunotherapy for hymenoptera allergy:
[A]
Children and adults with a history of a life-threatening reaction to a hymenoptera sting
[B]
People who have a history of a large local skin reaction that gets worse with each sting
[C]
Children with a history of generalized urticaria after a sting
[D]
Anyone with a family history of an allergic reaction to a hymenoptera sting
Answer: Children and adults with a history of a life-threatening reaction to a hymenoptera sting
51
Which of the following food allergies is most likely outgrown?
[A]
Milk
[B]
Peanut
[C]
Walnuts
[D]
Shellfish
52
Which of the following adverse drug reactions is believed to be due to IgEmediated mechanisms?
[A]
Aspirin induced anaphylaxis
[B]
Reaction to radiocontrast dye
[C]
Steven-Johnson’s Syndrome after a course of trimethoprim/sulfa
[D]
Wheezing, urticaria after administration of penicillin
Answer: Wheezing, urticaria after administration of penicillin
53
Hereditary angioedema is:
[A]
Inherited as an autosomal recessive disorder
[B]
Usually associated with urticaria
[C]
Usually responsive to antihistamines
[D]
Can be managed with Danazol (synthetic androgenic steroid)
Answer: Can be managed with Danazol (synthetic androgenic steroid)
54
In June, a 24-year-old female presents with angioedema of the face, including eyelids and lips. She has had two previous similar episodes. This episode, like the previous ones, occurred during the summer and was accompanied by diarrhea, low grade fever once and classical urticarial lesions.
[A]
Hereditary angioedema
[B]
Food allergy
[C]
Enterovirus infection
[D]
Idiopathic angioedema
Answer: Idiopathic angioedema
55
In June, a 24-year-old female presents with angioedema of the face, including eyelids and lips. She has had two previous similar episodes. She always has associated gas and diarrhea with the angioedema. She was previously skin tested and found to have sensitivities to milk, ragweed and molds. Which diagnosis is suggested?
[A]
Hereditary angioedema
[B]
Food allergy
[C]
Enterovirus infection
[D]
Idiopathic angioedema
56
In June, a 24-year-old female presents with angioedema of the face, including eyelids and lips. She has had two previous similar episodes. Her father has also had recurrent angiodema of the face and extremities. Neither has associated pruritis with the angioedema. Which diagnosis is suggested?
[A]
Hereditary angioedema
[B]
Food allergy
[C]
Enterovirus infection
[D]
Idiopathic angioedema
Answer: Hereditary angioedema
57
State one from airborne substances listed below is Seasonal allergen:
[A]
Dust mites
[B]
Cat dander
[C]
Ragweed
[D]
Perfume
58
State one from airborne substances listed below is Non-IgE mediated irritant:
[A]
Dust mites
[B]
Cat dander
[C]
Ragweed
[D]
Cigarette smoke
59
State one from airborne substances listed below is Perennial allergen:
[A]
Dust mites
[B]
Sagebrush
[C]
Ragweed
[D]
Perfume
60
Match the immune deficiency in Chronic Granulomatous disease with the appropriate lab test:
[A]
Quantitative immunoglobulins
[B]
CD11 by flow cytometry
[C]
NBT test (nitroblue tetrazolium test, oxidated burst)
[D]
Serum calcium
Answer: NBT test (nitroblue tetrazolium test, oxidated burst)
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