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Free download in PDF Immunology Objective Type Questions and Answers for competitive exams. These short objective type questions with answers are very important for Board exams as well as competitive exams. These short solved questions or quizzes are provided by Gkseries.
(21)
An 8-year-old male has asthma symptoms about three times per month requiring the use of an albuterol inhaler, despite adequate inhaled steroid treatment. These episodes typically occur at night. The child is not allergic to his guinea pig or dust mites, and there is no smoking in the home. He has no problems with exercise and rarely needs albuterol during the day except when he has an upper respiratory tract viral infection. His FEV1 and PEFR are both >80% predicted. Based on this history, the most likely trigger for his nighttime asthma is:
[A]
Allergic rhinitis
[B]
Obstructive sleep apnea
[C]
Gastro-esophageal reflux disease (GERD)
[D]
None of the above
Answer: Gastro-esophageal reflux disease (GERD)
(22)
A 45-year-old woman with a strong family history of both allergies and glaucoma presents with frequent red eyes that sometimes itch, sometimes feel dry and sometimes water. On exam, bulbar conjunctivae are injected, palpebral conjunctiva are normal in color. Nasal mucosa is moderately swollen and pale.
Which of the following is the most likely diagnosis?
[A]
Vernal conjunctivitis
[B]
Allergic conjunctivitis
[C]
Glaucoma
[D]
Dryness from hormone replacement
Answer: Allergic conjunctivitis
(23)
A 5-year-old boy lives in a smoking household and has a history of RSV bronchiolitis in infancy. He has been diagnosed with bronchitis at least once, and sometimes twice, every winter. He has sneezing and allergic salute in spring and fall. When he runs in kindergarten he often coughs but has no obvious shortness of breath. He wakes at night coughing only when he has bronchitis. He is unable to do full pulmonary functions. The historical information most suggestive of asthma in this child is:
[A]
Cough at night when ill
[B]
His allergic symptoms
[C]
RSV bronchiolitis in infancy
[D]
Cough with exercise
Answer: Cough with exercise
(24)
The one true statement about anaphylaxis is
[A]
There are always skin findings—rash, angioedema, etc.
[B]
People with recurrent anaphylaxis with no identifiable cause (idiopathic) are the most likely to carry adrenalin
[C]
After adrenalin, the most important medication to administer immediately is steroids
[D]
The most likely patient to die of anaphylaxis has underlying asthma
Answer: After adrenalin, the most important medication to administer immediately is steroids
(25)
A 2-year-old with wheezing, persistent cough, a history of vomiting with cough, as well as hives and angioedema and increased cough after milk products comes to your office for evaluation. He drinks soy and grandma is not feeding him any milk products. He has been treated with prn albuterol nebulizer treatments with benefit in the past. On exam he has frequent congested cough, p = 112, r =26, shiners and Dennies lines. On chest exam he has transmitted upper airway rhonchi and coarse breath sounds but no wheezes or rales. Nasal exam reveals swollen pale nasal mucosa without any visible discharge. CXR shows increased bronchovascular markings without infiltrate but with hyperexpansion. What diagnostic lab information do you want to obtain?
[A]
CBC and diff, IgE and IgG RAST to milk and soy
[B]
CBC and diff, total IgE, IgG RAST to milk
[C]
CBC and diff, total IgE, and skin or RAST testing to milk, casein and soy
[D]
CBC, milk precipitins, IgE RAST to milk and casein
Answer: CBC and diff, total IgE, and skin or RAST testing to milk, casein and soy
(26)
The most common cause of contact dermatitis in general is:
[A]
Latex
[B]
Poison ivy, poison oak and poison sumac
[C]
Nickel
[D]
None of the above
Answer: Poison ivy, poison oak and poison sumac
(27)
The two most common superinfections in atopic dermatitis are due to:
[A]
Staph aureus and Herpes simplex
[B]
Staph epidermidis and cutaneous viral infections
[C]
Staph aureus and Candida
[D]
Staph epidermidis and Candida
Answer: Staph aureus and Herpes simplex
(28)
Common causes of acute urticaria include all of the following except:
[A]
Food allergy
[B]
Drug allergy
[C]
Viral infection
[D]
Inhalant allergy
(29)
Hereditary angioedema (C1 inhibitor deficiency) is characterized by all of the following except:
[A]
Frequent abdominal pain
[B]
Urticaria or hives
[C]
Low C4 levels during and between attacks
[D]
Family history of swelling
Answer: Urticaria or hives
(30)
Which of the following would not suggest a FISH (Fluorescence In Situ Hybridization) test to identify DiGeorge syndrome?
[A]
Recurrent otitis media in a 3-year-old
[B]
Neonatal tetany
[C]
Pervasive developmental delay in a 6-year-old female
[D]
Recurrent/persistent otitis and diarrhea in a 6-month-old
Answer: Pervasive developmental delay in a 6-year-old female
31
Which of the following symptoms is least common in patients with sinusitis?
[A]
Nasal congestion
[B]
Cough
[C]
Fever
[D]
“Post-nasal” drip
32
A 40-year-old male presents to the Emergency Room complaining of hives, wheezing and difficulty breathing following an insect sting. Pulse is 120 beats/min. BP is 100/56. After Epinephrine is administered and quick assessment of the patient is done, you determine that the patient is moving air adequately and is not in shock. The next medication to give the patient immediately is:
[A]
Diphenhydramine 50 mg IV
[B]
Methylprednisolone 100 mg IV
[C]
Epinephrine 0.3 ml (1:1000 aqueous) sub Q or IM
[D]
Cholorpheniramine 8 mg orally
Answer: Methylprednisolone 100 mg IV
33
A 40-year-old male presents to the Emergency Room complaining of hives,wheezing and difficulty breathing following an insect sting. Pulse is 120 beats/min.BP is 100/56. Immediate therapy should include which one of the following:
[A]
Diphenhydramine 50 mg IV
[B]
Methylprednisolone 100 mg IV
[C]
Epinephrine 0.3 ml (1:1000 aqueous) sub Q or IM
[D]
Cholorpheniramine 8 mg orally
Answer: Epinephrine 0.3 ml (1:1000 aqueous) sub Q or IM
34
Inhaled corticosteroids (Choose the one incorrect answer):
[A]
Can be useful in patients who have persistent asthma
[B]
Can be useful in patients who require rescue inhaler 1-2 times per week
[C]
Can be used in 6-12 year-old children with asthma
[D]
Acutely increase peak flow rate, a measure of large airway function
Answer: Acutely increase peak flow rate, a measure of large airway function
35
Which of the following is the most common underlying cause of asthma?
[A]
Beta Blocker sensitivity
[B]
Aspirin sensitivity
[C]
Bronchitis
[D]
Inhalant allergies
Answer: Inhalant allergies
36
Conditions which may worsen asthma include (Identify the one incorrect choice):
[A]
Diabetes Mellitus
[B]
Sinusitis
[C]
Pregnancy
[D]
Cardiac disease
Answer: Diabetes Mellitus
37
Which of the following tests would be most useful in helping to diagnose asthma:
[A]
Diffusing capacity
[B]
Pre and post bronchodilator FEV1
[C]
Pulmonary functions pre- and post-methacholine challenge
[D]
B and C
38
All of the following regarding aspirin intolerance are true except:
[A]
Patients with asthma are at no greater risk for aspirin intolerance than the general population
[B]
A proposed mechanism of aspirin intolerance involves aspirin’s effect on arachidonic acid metabolism
[C]
There is cross reactivity between aspirin and NSAID intolerance
[D]
Aspirin desensitization may be of benefit in a patient with aspirin intolerance who requires the drug
Answer: Patients with asthma are at no greater risk for aspirin intolerance than the general population
39
All of the following except one can be useful in managing atopic dermatitis:
[A]
Skin lubrication/moisturization
[B]
Controlling pruitus to reduce scratching
[C]
Immunotherapy (allergy injections)
[D]
Avoiding specific food allergy triggers
Answer: Immunotherapy (allergy injections)
40
Congenital complement deficiencies are best screened by which of the following laboratory tests:
[A]
Quantitative immunoglobulins
[B]
NBT
[C]
Total CH50
[D]
C3, C4 and properdin
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