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Molecular Biology Techniques MCQs | Molecular Biology Techniques Multiple Choice Questions and Answers

(1) Southern Hybridization is
[A] Used To Identify A Specific DNA
[B] Used To Identify Both DNA And RNA
[C] Used To Identify A Specific Protein
[D] Used To Identify A Specific RNA
Answer: Used To Identify A Specific DNA
(2) Applications Of Southern Blotting Includes
[A] Identification Of Transferred Genes
[B] DNA Fingerprinting
[C] Preparation Of RFLP Maps
[D] All Of These
Answer: All Of These

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(3) First DNA Glycosylase Enzyme Discovered Is ___________.
[A] Thymine DNA Glycosylase
[B] Adenine DNA Glycosylase
[C] Methyl Adenine Glycosylase
[D] Uracil DNA Glycosylase
Answer: Uracil DNA Glycosylase
(4) The Enzyme Photolyase Repair The Thymine Dimer In The DNA By __________ Mechanism.
[A] Free Radical Mechanism
[B] Adduct Formation
[C] Oxidation Mechanism
[D] Direct Bond Breaking
Answer: Free Radical Mechanism
(5) The Function Of Uvrc In NER Mechanism Is_________.
[A] Catalyze The Incision At The 3’ End Of The Lesion
[B] Catalyze The Incision At The 5’ Side Of The Lesion
[C] To Identify The Lesion In The DNA
[D] Helicase Activity To Unwind The DNA
Answer: Catalyze The Incision At The 5’ Side Of The Lesion
(6) The Catalytic Activity Of Photolyase Enzyme In The Bacterial Cells Is Activated By _____.
[A] Visible Light Near Blue Region
[B] Visible Light Near Red Region
[C] IR Light
[D] UV Light
Answer: Visible Light Near Blue Region
(7) Photolyase Enzyme Involved In The Photoreactivation Can Remove ______.
[A] UV Induced Thymine Dimers
[B] Single Strand Breaks In DNA
[C] UV Induced Double Strand Breaks
[D] Mismatches In DNA
Answer: UV Induced Thymine Dimers
(8) Which Of The Following Gene Is NOT Involved In Mismatch Repair System In Bacteria?
[A] Mutl
[B] Muts
[C] Muta
[D] None of these
Answer: Muta
(9) Which Enzyme Is Responsible For Photoreactivation Of DNA:
[A] Photolyase
[B] Photo-Oxidase
[C] Photoligase
[D] Photoreductase
Answer: Photolyase
(10) Which Of The Following DNA Repair Mechanism Is Known As The ‘Cut And Patch Mechanism’?
[A] Nucleotide Excision Repair
[B] Mismatch Repair
[C] Photoreactivation
[D] None of these
Answer: Nucleotide Excision Repair
(11) Which Of The Following Enzyme(S) Is Involved Base Excision Repair?
[A] DNA Glycosylase
[B] AP Endonuclease
[C] AP Exonuclease
[D] Both (A) And (B)
Answer: Both (A) And (B)
(12) The Technique Used To Identify Specific DNA Sequence In Bacterial Colonies Is
[A] Western Blotting
[B] Dot Blot Technique
[C] In Situ Hybridization
[D] Colony Hybridization
Answer: Colony Hybridization
(13) Which Of The Following Statements Are True Regarding Southern Blotting
[A] DNA-DNA Hybridization Is The Basis
[B] The Transfer Of DNA Fragments From Gel To Nitrocellulose Membrane Is Called Blotting
[C] Developed By E.M.Southern
[D] All Of These
Answer: All Of These
(14) The Technique Used To Detect The Presence Of DNA Or RNA In A Non-Fractionated DNA Sample Is
[A] Dot Blot Technique
[B] Western Blotting
[C] Colony Hybridization
[D] None of these
Answer: Dot Blot Technique
(15) Northern Hybridization Is
[A] Used To Identify Both DNA And RNA
[B] Used To Identify A Specific RNA
[C] Used To Identify A Specific Protein
[D] Used To Identify A Specific DNA
Answer: Used To Identify A Specific RNA
(16) Southern Hybridization is
[A] Used To Identify Both DNA And RNA
[B] Used To Identify A Specific DNA
[C] Used To Identify A Specific RNA
[D] Used To Identify A Specific Protein
Answer: Used To Identify A Specific DNA
(17) For Glycoproteins, Most Commonly Used Probe Is
[A] Interferons
[B] Antigens
[C] Lectin
[D] Antibody
Answer: Lectin
(18) ELISA Is Based On
[A] Lectin- Antibody Interaction
[B] Antigen-Protein Intercation
[C] Antigen-Antibody Interaction
[D] All Of These
Answer: Antigen-Antibody Interaction
(19) The Technique Used To Locate Specific Genes In Chromosomes Is
[A] Colony Hybridization
[B] Dot Blot Technique
[C] Western Blotting
[D] In Situ Hybridization
Answer: In Situ Hybridization
(20) The Separation Technique Of Charged Molecules Under The Influence Of Electric Current Is Called
[A] Western Blotting
[B] Colony Hybridization
[C] Dot Blot Technique
[D] Electrophoresis
Answer: Electrophoresis

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