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NCERT - Biotechnology Principles and Processes Questions and Answers of Class 12 Biology | GkSeries

(16) The most important feature in a plasmid to be used as a vector is:
[1] Origin of replication (ori)
[2] Presence of a selectable marker
[3] Presence of sites for restriction endonuclease
[4] Its size
Answer: Origin of replication (ori)
(17) An enzyme catalysing the removal of nucleotides from the ends of DNA is:
[1] endonuclease
[2] exonuclease
[3] DNA ligase
[4] Hind – II
Answer: exonuclease

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(18) A bacterial cell was transformed with a recombinant DNA that was generated using a human gene. However, the transformed cells did not produce the desired protein. Reasons could be:
[1] Human gene may have intron which bacteria cannot process
[2] Amino acid codons for humans and bacteria are different
[3] Human protein is formed but degraded by bacteria
[4] All of the above
Answer: Human gene may have intron which bacteria cannot process
(19) Transgenic organisms means
[1] An organism with all desirable characters
[2] an organism with a particular mutated gene
[3] an organism with foreign gene by genetic engineering
[4] An organism with a number of mutated characters.
Answer: an organism with foreign gene by genetic engineering
(20) Gene cloning means
[1] Production of mutated genes
[2] Production of wild genes
[3] Production of dominant genes
[4] production of large populations of desired DNA fragments
Answer: production of large populations of desired DNA fragments
21 Molecular scissors are
[1] Ligase
[2] Helicase
[3] Restriction endonuclease
[4] DNA polymerase
Answer: Restriction endonuclease
22 For DNA finger printing we need
[1] cells from the tip of finger
[2]
[3] cells from the reproductive organs
[4] any cells from the fingers
Answer: cells from any part of the body
23 Which of the following has popularised the PCR (polymerase chain reactions)?
[1] Easy availability of DNA template
[2] Availability of synthetic primers
[3] Availability of cheap deoxyribonucleotides
[4] Availability of ‘Thermostable’ DNA polymerase
Answer: Availability of ‘Thermostable’ DNA polymerase
24 The role of DNA ligase in the construction of a recombinant DNA molecule is:
[1] Formation of phosphodiester bond between two DNA fragments
[2] Formation of hydrogen bonds between sticky ends of DNA fragments
[3] Ligation of all purime and pyrimidine bases
[4] None of the above
Answer: Formation of phosphodiester bond between two DNA fragments
25 Artificial synthesis of DNA without a template was first done by
[1] Khorana
[2] Geier
[3] Meselson
[4] Watson
Answer: Khorana
26 Genetically modified DNA fragments are called
[1] Recombinant DNA
[2] S DNA
[3] Mitochondrial DNA
[4] None of these
Answer: Recombinant DNA
27 Which of the given statement is correct in the context of observing DNA separated by agarose gel electrophoresis?
[1] DNA can be seen in visible light
[2] DNA can be seen without staining in visible light
[3] Ethidium bromide stained DNA can be seen in visible light
[4] Ethidium bromide stained DNA can be seen under exposure to UV light
Answer: Ethidium bromide stained DNA can be seen under exposure to UV light
28 An antibiotic resistance gene in a vector usually helps in the selection of:
[1] Competent cells
[2] Transformed cells
[3] Recombinant cells
[4] None of the above
Answer: Transformed cells
29 Totipotency means
[1] Ability of a cell to grow into a complete plant
[2] Ability of an animal cell to recombine with plant cell
[3] Ability of a cell to grow into a complete individual
[4] Ability of an animal cell to fully developed animal cell
Answer: Ability of a cell to grow into a complete individual
30 Which one is a true statement regarding DNA polymerase used in PCR?
[1] It is isolated from a virus
[2] It remains active at high temperature
[3] It is used to ligate introduced DNA in recipient cells
[4] It serves as a selectable marker
Answer: It remains active at high temperature

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