Translation MCQs | Translation Multiple Choice Questions and Answers

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Questions
1 Genetic code is
A The Sequence Of Nitrogenous Bases In Mrna Molecule That Codes For A Protein
B Is A Triplet Code
C Is Non-Overlapping
D All Of These

Answer: Is A Triplet Code
2 Translation is the
A synthesis of DNA from a mRNA template
B synthesis of protein from a mRNA template
C synthesis of RNA from a mRNA template
D synthesis of RNA from a DNA template

Answer: synthesis of protein from a mRNA template
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3 Translation occurs in the
A nucleus
B cytoplasm
C nucleolus
D lysosome

Answer: cytoplasm
4 Which of the following RNA molecules serves as an adaptor molecule during protein synthesis
A rRNA
B mRNA
C tRNA
D tRNA and mRNA

Answer: tRNA
5 Which is the energy rich molecule required for initiation of translation
A ATP
B GTP
C CTP
D None of the above

Answer: GTP
6 The eukaryotic initiation codon recognizes________
A f-Met-tRNA-f-Met
B Met-tRNAi-Met
C f-Met-tRNAi-Met
D f-Met-tRNA-Met

Answer: f-Met-tRNAi-Met
7 What is the final factor in eukaryotes that releases the peptide and ribosome?
A eRRF
B EF2
C RF3
D RF4

Answer: RF3
8 In Eukaryotes the region between 1st AUG and 5’-G cap is known as ___________
A Leader
B Attenuator
C UTR
D ORF

Answer: UTR
9 IRE-BP does not bind to _______________
A IRES
B Stem loop in 5’ end of Ferritin
C Stem loop in 3’ end of Transferrin
D AU rich regions in IRE

Answer: IRES
10 The pentose sugar moieties are the primary structural difference between DNA and RNA. In addition which of the following is primarily associated with RNA molecule?
A RNA consist of thymine instead of uracil
B RNA molecules are highly branched structure
C RNA molecules have higher structural complexities
D RNA molecules are anti-parallel and double-stranded

Answer: RNA consist of thymine instead of uracil
11 In prokaryotes, a holoenzyme RNA polymerase consists of four core subunits namely 2α, 1β, 1β' and a promoter recognizing σ subunit. It may also require a termination factor for termination of the transcription factor. Which of the following is a transcription factor?
A gamma factor
B delta factor
C epsilon factor
D rho factor

Answer: rho factor
12 In eukaryotes, three different RNA polymerases are involved in the synthesis of a different class of RNAs namely: rRNA, tRNA, and mRNA. The RNA polymerase that is required for the synthesis of mRNA is
A RNA polymerase I
B RNA polymerase II
C RNA polymerase III
D None of the above

Answer: RNA polymerase II
13 The capping of nucleotide prevents the rapid cleavage of mRNA and catalyzed by guanylyltransferase. Identify the nucleotide cap that is attached at the 5'end of mRNA.
A 5-methyl guanosine
B 7- methyl guanosine
C 5- acetyl guanosine
D 7- acetyl guanosine

Answer: 7- methyl guanosine
14 The auto-antibodies against the small nucleoproteins are present in
A beta thalassemia
B systemic lupus erythematosus
C Phenylketonuria
D None of the above

Answer: systemic lupus erythematosus
15 CAAT box is present in many
A Prokaryotic promoters upstream of TATA box
B Prokaryotic promoters are downstream of TATA box
C Eukaryotic promoters are upstream of TATA box
D Eukaryotic promoters are downstream of TATA box

Answer: Prokaryotic promoters upstream of TATA box
16 The antibody binding diversity is a result of a type splicing that produces mRNA variants and protein variants by processing different segment of exons. The process is known as
A Diversity splicing
B Alternative splicing
C Conservative splicing
D None of the above

Answer: Alternative splicing
17 The role of small nuclear ribonucleoprotein particles (snRNPs) is
A to bind intronic sites and exon segments
B facilitate the looping of the two exons into the correct alignment for splicing
C All of the above
D None of the above

Answer: All of the above
18 In eukaryotes, the primary transcripts are processed to remove intervening sequence resulting in mRNA and the process is known as splicing. The complex of RNA, nucleoproteins that execute splicing process is called:
A Primosome
B Splicing fork
C Spliceosome
D None of the above

Answer: Spliceosome
19 The polyadenylation is a post transcription modification that stabilizes the mRNA and prevent from the cleavage. The consensus PolyA sequence is
A (AAGAAA)n
B (AACAAA)n
C (AATAAA)n
D (AAUAAA)n

Answer: (AAUAAA)n
20 Enhancers are special cis-acting DNA sequences that increase the rate of transcription by RNA polymerase. Which of the following is true regarding enhancers?
A 10 nucleotide upstream elements
B 25 nucleotide downstream elements
C present closer or 1000s nucleotide upstream or downstream of TSS
D All of the above

Answer: present closer or 1000s nucleotide upstream or downstream of TSS

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