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Molecular Basis of Inheritance MCQs | Molecular Basis of Inheritance Multiple Choice Questions (MCQs) and Answers

(1) With respect to microsatellite DNA which of the following is correct?
[A] Tandem repeats
[B] Dinucleotide repeats
[C] 100 bp units
[D] Inaccurate duplicating
Answer: 100 bp units
(2) Genome – wide repeat unit are generally transposable elements.
[A] True
[B] False
Answer: True
(3) Repeated DNA can be referred to as junk DNA.
[A] True
[B] False
Answer: False
(4) The simpler the organism the more likely they are to have transposable elements.
[A] True
[B] False
Answer: False
(5) Double-stranded structure of nucleic acid is the basic requirement for palindromic sequences.
[A] True
[B] False
Answer: True
(6) Which of the following words represents a palindrome?
[A] DUCK
[B] MAMA
[C] BOOM
[D] MADAM
Answer: MADAM
(7) Which of the following will form a palindromic sequence?
[A] ATTGCAAT
[B] AGTCCTGA
[C] GTTCCAAG
[D] GTTGGAAC
Answer: ATTGCAAT
(8) Which of the following is affected by palindromic sequences?
[A] Acetylation site
[B] Phosphorylation site
[C] Methylation site
[D] Promoter site
Answer: Methylation site
(9) Palindromic sequences play a very important role in gene manipulation.
[A] True
[B] False
Answer: True
(10) Which of the following palindromes is not a restriction site?
[A] GAATTC
[B] TACGTA
[C] CCTAGG
[D] AGCT
Answer: TACGTA
(11) Molecular cutters do not recognize the palindromic sequence.
[A] True
[B] False
Answer: False
(12) Which of the following is an example of an inverted repeat?
[A] ATTCGCGAAT
[B] ATCGNNNNCGAT
[C] TACCNNNNGGAT
[D] AGCCNNNCCGA
Answer: ATCGNNNNCGAT
(13) Inverted repeat have a number of biological functions. Which of the following is a biological function of an inverted repeat?
[A] Diseases
[B] Central dogma
[C] Cellular metabolism
[D] Genetic stability
Answer: Diseases
(14) Most commonly known hairpin structures are found in _____________
[A] DNA
[B] mRNA
[C] tRNA
[D] rRNA
Answer: tRNA
(15) Which of the following does not promote stability in stem-loop structure?
[A] Length of the stem
[B] Size of the loop
[C] A : U base pairing
[D] π orbital of aromatic ring
Answer: A : U base pairing
(16) What is the minimum number of bases required for loop stability?
[A] 2
[B] 3
[C] 4
[D] 5
Answer: 3
(17) Which of the following does not contain a stem-loop structure?
[A] tRNA
[B] Pseudoknot
[C] Ribozyme
[D] rRNA
Answer: rRNA
(18) Which of the following cannot be used for the separation of nucleic acids?
[A] SDS – PAGE
[B] PAGE
[C] Northern blotting
[D] PAGE
Answer: SDS – PAGE
(19) The polymerization of the gel used in PAGE occurs between polyacrylamide and ____________
[A] N, N – acrylamide
[B] Bisacrylamide
[C] N – methyleneacrylamide
[D] N, N – methylene bisacrylamide
Answer: N, N – methylene bisacrylamide
(20) If DNA is digested by endonucleases in four sites giving rise to fragments of which two are equal in length how many bands would be seen after electrophoresis?
[A] 3
[B] 4
[C] 5
[D] 6
Answer: 4

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