GkSeries.com

Molecular Basis of Inheritance MCQs | Multiple Choice Questions with Answers on Molecular Basis of Inheritance

(1) Fredrick Griffith’s experiment involving Streptococcus pneumonia lead to the discovery of____________
[A] DNA as genetic material
[B] RNA as genetic material
[C] Protein as genetic material
[D] Transforming principle
Answer: Transforming principle
(2) Definite results proving DNA to be genetic material was given by __________
[A] Fredrick Griffith
[B] Hershey and Chase
[C] Avery, Macleod and MacCarty
[D] Meselson and Stahl
Answer: Avery, Macleod and MacCarty
(3) Which of the following statements regarding the mechanism of transformation in Bacillus subtilis is false?
[A] A competent bacteria contains a DNA receptor/translocation complex
[B] While translocation of exogenous DNA, both strands gets passage into the cell
[C] While translocation of exogenous DNA, only one strand gets passage into the cell
[D] The exogenous DNA recombines and incorporates itself in the chromosome of the recipient cell
Answer: While translocation of exogenous DNA, both strands gets passage into the cell
(4) What were the main criteria taken under consideration for the experiment by Hershey and Chase?
[A] DNA contains phosphorus, protein contains sulfur
[B] Protein contains phosphorus, DNA contains sulfur
[C] Both DNA and protein contains phosphorus and not sulphur
[D] Both DNA and protein contains sulfur and not phosphorus
Answer: DNA contains phosphorus, protein contains sulfur
(5) What combination of radiolabelling is correct in case of Hershey and Chase’s demonstration of DNA as genetic material in T2 bacteriophage?
[A] 31P, 35S
[B] 31P, 32S
[C] 31P, 14C
[D] 31P, 12C
Answer: 31P, 35S
(6) Recently, scientists have developed a procedure in which protoplasts of E. coli could be directly infected with the phage DNA. This process is termed as_________
[A] Transformation
[B] Transduction
[C] Transfection
[D] Mutation
Answer: Transfection
(7) According to Mendel’s experiments gene carry genetic information from parents to offspring’s. On which plant did he perform his experiments?
[A] Oryza sativa
[B] Pisum sativam
[C] Allium cepa
[D] Vitis vinifera
Answer: Pisum sativam
(8) Plasmids are ____________
[A] Double stranded DNA
[B] Circular double stranded DNA
[C] Linear double stranded DNA
[D] Supercoiled circular double stranded DNA
Answer: Circular double stranded DNA
(9) What stores the genetic information in DNA?
[A] Sugar
[B] Phosphate
[C] Nitrogenous base
[D] Polymerase
Answer: Nitrogenous base
(10) DNA always carries the genetic information for all organisms.
[A] True
[B] False
Answer: False
(11) What is the major type of RNA produced in the cell required for translation?
[A] mRNA
[B] tRNA
[C] rRNA
[D] siRNA
Answer: rRNA
(12) Which macromolecule is not abundantly found though being of critical importance for biological mechanisms?
[A] Proteins
[B] Lipids
[C] Nucleic acids
[D] Polysaccharides
Answer: Lipids
(13) Which of the following is wrongly paired?
[A] Proteins – peptide bond
[B] Nucleic acid – hydrogen bond
[C] Polysaccharide – glycosidic bond
[D] Phospholipids –phosphate linkage
Answer: Nucleic acid – hydrogen bond
(14) With respect to nucleosides which of the following is paired correctly?
[A] Purine – Adenosine, Thymidine
[B] Purine – Guanosine, Thymidine
[C] Pyrimidine – Uridine, Cytidine
[D] Pyrimidine – Uridine, Adenosine
Answer: Pyrimidine – Uridine, Cytidine
(15) Which of the following is not a component of the nucleic acid backbone?
[A] Pentose sugar
[B] Phosphate group
[C] Nucleotide
[D] Phosphodiesterase bond
Answer: Nucleotide
(16) According to Chargaff’s rule the two strands of DNA has ___________
[A] Same molecular weight
[B] Same amount of A and G
[C] Different amount of A and G
[D] Different molecular weight
Answer: Different molecular weight
(17) In one strand of a double stranded DNA the rate of occurrence of A is 3 times C in consecutive 10 bases. So how many G will be there in 100 base pairs of a DNA duplex?[Consider G=T in one strand].
[A] 30
[B] 20
[C] 40
[D] 60
Answer: 40
(18) In a diploid organism with 30,000 bases haploid genome contains 23% A residues. What is the number of G residues in the genome of this organism?
[A] 16000
[B] 16200
[C] 16500
[D] 14200
Answer: 16200
(19) Which of the following is not a characteristic of nucleotide bases?
[A] Planar
[B] Heterocyclic
[C] Aliphatic
[D] Ubiquitous
Answer: Pleiotropism
(20) Which of the following factors do not provide to the separation of DNA fragments during electrophoresis?
[A] Chargaff’s rule
[B] Matrix density
[C] Ethidium bromide
[D] Size
Answer: Ethidium bromide

Please share this page

Click Here to Read more questions

Teacher Eligibility Test