Molecular Basis of Inheritance MCQs | GK Questions and Answers on Molecular Basis of Inheritance

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Questions
1 Binding of polymerase III and helicase ensures helicase efficiency.
A True
B False

Answer:True
2 Association of primase with DNA template is brought about by the interaction of primase with _________________
A Dna polymerase III
B Clamp-loader complex
C Helicase and SSB protein
D τ protein

Answer:Helicase and SSB protein
3 How is the strength of the interaction between primase and helicase which regulates the length of Okazaki fragments?
A Weak association short fragment
B Strong association short fragment
C Strong association long fragment
D Does not depend on strength of association

Answer: Strong association short fragment
4 Which of the following enzyme is not required for the synthesis of lagging strand?
A Primase
B Gyrase
C Helicase
D Exonuclease

Answer:Gyrase
5 Length of Okazaki fragments in eukaryotes ranges between ____________ nucleotides.
A 100 – 400
B 400 – 800
C 800 – 1200
D 1200 – 1600

Answer: 100 – 400
6 Polymerization of dNTP by DNA polymerase is in 3’ → 5’ direction.
A True
B False

Answer:False
7 Polymerization of dNTP by DNA polymerase is in 3’ → 5’ direction.
A True
B False

Answer: False
8 The origin of replication is rich in __________
A A, T
B G, C
C A, G
D C, T

Answer:A, T
9 How many origin of replication are present in the E. coli genome ___________
A 1
B 100
C Uncountable
D None

Answer:1
10 There are two repeated motifs critical for ori C function. They are ___________
A 9 mer and 18 mer
B 6 mer and 9 mer
C 9 mer and 13 mer
D 13 mer and 18 mer

Answer:9 mer and 13 mer
11 With respect to the ori C motif choose the correctly paired option.
A 9 mer = 9 times
B 9 mer = 3 times
C 13 mer = 5 times
D 13 mer = 3 times

Answer:13 mer = 3 times
12 Which of the following is not paired with its correct function?
A 9 mer = binding site for Dna A
B 13 mer = binding site for replication initiator protein
C AT rich DNA = unwinding site
D Dna A = replication initiator protein

Answer: 13 mer = binding site for replication initiator protein
13 Which of the following is not a function of Dna A?
A DNA binding
B DNA strand separation
C Initiates DNA melting
D Replication protein recruitment

Answer:Initiates DNA melting
14 The replication terminus is a segment of a number of ____________ bp.
A 350
B 350000
C 530
D 530000

Answer: 350000
15 The replication terminus involves ____________ identical non palindromic termination site.
A 2
B 4
C 6
D 8

Answer:6
16 The termination sites are one way valves known as non-polar valves.
A True
B False

Answer:False
17 The arrest of replication fork motion at Ter sites require the action of ____________ protein.
A Tus
B Ter
C Helicase
D Topoisomerase

Answer:Tus
18 The topological unlinking of DNA in prokaryotes is promoted by ______________
A Helicase
B Topoisomerase
C Tus
D Dna C

Answer:Topoisomerase
19 Helicase attaches to the leading strand during replication.
A True
B False

Answer: False
20 The primer used for lagging strand synthesis in prokaryotes is an RNA primer.
A True
B False

Answer: False

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