Molecular Basis of Inheritance MCQs | GK Questions with Answers on Molecular Basis of Inheritance

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Questions
1 Which enzyme is used to remove the primer from the Okazaki fragment?
A Endonuclease
B RNase H
C 5’ exonuclease
D Polymerase

Answer:Polymerase
2 Who of the following was not one of the scientists explaining the replicon model?
A Francois Jacob
B Sydney Brenner
C Jacques Cuzin
D Arthur Kornberg

Answer: Arthur Kornberg
3 The replicon model was first explained in the year ____________
A 1950
B 1957
C 1963
D 1968

Answer: 1963
4 The eukaryotic chromosome has a single replicon.
A True
B False

Answer:False
5 The replicon model comprises of an initiator and _______________
A Replicator
B Origin of replication
C Dna A protein
D AT rich DNA

Answer: Replicator
6 Replicator is the synonym for origin of replication.
A True
B False

Answer:Muton
7 The initiator protein binds to a segment ____________ of the replicator sequence.
A Upstream
B Downstream
C At the end
D Within

Answer: Within
8 Binding of the Dna A protein to the DNA is energy dependent.
A True
B False

Answer:True
9 Assembly of how many proteins make up the origin replication complex (ORC) in eukaryotes?
A 2
B 4
C 6
D 8

Answer:6
10 Which of the following proteins is not recruited by Dna A protein?
A Dna A protein
B Helicase
C Dna C protein
D SSB protein

Answer:SSB protein
11 Replication of chromosome occurs during the ____________ phase.
A G1
B S
C G2
D Division

Answer:S
12 It is important to replicate the DNA correctly and only once.
A True
B False

Answer: True
13 Selection of replicator occurs in ___________ phase.
A G1
B S
C G2
D Division

Answer: G1
14 Activation of the origin of replication occurs in ____________ phase.
A G1
B S
C G2
D Division

Answer: S
15 The replicator selection is mediated by the formation of pre-replicative complex. It comprises of _________________
A ORC and the initiator protein
B ORC and helicase
C A helicase loader and a helicase
D An ORC, two helicase loaders and a helicase

Answer:An ORC, two helicase loaders and a helicase
16 The pre – RCs are auto-activated as soon as the cell enters the S – phase.
A True
B False

Answer:False
17 Which of the following is wrong about the cyclin dependent kinases?
A Phosphorylates enzymes
B Activates pre – RCs
C Promotes formation of new pre – RCs
D Activates in the S – phase

Answer:Promotes formation of new pre – RCs
18 Active cyclin dependent kinase is absent in ____________ phase.
A G1
B S
C G2
D Division

Answer:G1
19 A sample of DNA contains 20% of adenine. What is the quantity of guanine present?
A 30
B 20
C 15
D 25

Answer: 20
20 Who proposed the concept of reverse transcription?
A Crick & Temmin
B Temmin & Baltimore
C Watson & Chargaff
D Chargaff

Answer: Temmin & Baltimore

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