Multiple Choice Questions with Answers on Molecular Basis of Inheritance

1 Fredrick Griffith’s experiment involving Streptococcus pneumonia lead to the discovery of____________

A DNA as genetic material

B RNA as genetic material

C Protein as genetic material

D Transforming principle

View Answer

Answer:Transforming principle

2 Definite results proving DNA to be genetic material was given by __________

A Fredrick Griffith

B Hershey and Chase

C Avery, Macleod and MacCarty

D Meselson and Stahl

View Answer

Answer: Avery, Macleod and MacCarty

3 Which of the following statements regarding the mechanism of transformation in Bacillus subtilis is false?

A A competent bacteria contains a DNA receptor/translocation complex

B While translocation of exogenous DNA, both strands gets passage into the cell

C While translocation of exogenous DNA, only one strand gets passage into the cell

D The exogenous DNA recombines and incorporates itself in the chromosome of the recipient cell

View Answer

Answer:While translocation of exogenous DNA, both strands gets passage into the cell

4 What were the main criteria taken under consideration for the experiment by Hershey and Chase?

A DNA contains phosphorus, protein contains sulfur

B Protein contains phosphorus, DNA contains sulfur

C Both DNA and protein contains phosphorus and not sulphur

D Both DNA and protein contains sulfur and not phosphorus

View Answer

Answer: DNA contains phosphorus, protein contains sulfur

5 What combination of radiolabelling is correct in case of Hershey and Chase’s demonstration of DNA as genetic material in T2 bacteriophage?

A 31P, 35S

B 31P, 32S

C 31P, 14C

D 31P, 12C

View Answer

Answer: 31P, 35S

6 Recently, scientists have developed a procedure in which protoplasts of E. coli could be directly infected with the phage DNA. This process is termed as_________

A Transformation

B Transduction

C Transfection

D Mutation

View Answer

Answer: Transfection

7 According to Mendel’s experiments gene carry genetic information from parents to offspring’s. On which plant did he perform his experiments?

A Oryza sativa

B Pisum sativam

C Allium cepa

D Vitis vinifera

View Answer

Answer: Pisum sativam

8 Plasmids are ____________

A Double stranded DNA

B Circular double stranded DNA

C Linear double stranded DNA

D Supercoiled circular double stranded DNA

View Answer

Answer:Circular double stranded DNA

9 What stores the genetic information in DNA?

A Sugar

B Phosphate

C Nitrogenous base

D Polymerase

View Answer

Answer:Nitrogenous base

10 DNA always carries the genetic information for all organisms.

A True

B False

View Answer

Answer: False

11 What is the major type of RNA produced in the cell required for translation?

A mRNA

B tRNA

C rRNA

D siRNA

View Answer

Answer:rRNA

12 Which macromolecule is not abundantly found though being of critical importance for biological mechanisms?

A Proteins

B Lipids

C Nucleic acids

D Polysaccharides

View Answer

Answer: Lipids

13 Which of the following is wrongly paired?

A Proteins – peptide bond

B Nucleic acid – hydrogen bond

C Polysaccharide – glycosidic bond

D Phospholipids –phosphate linkage

View Answer

Answer: Nucleic acid – hydrogen bond

14 With respect to nucleosides which of the following is paired correctly?

A Purine – Adenosine, Thymidine

B Purine – Guanosine, Thymidine

C Pyrimidine – Uridine, Cytidine

D Pyrimidine – Uridine, Adenosine

View Answer

Answer: Pyrimidine – Uridine, Cytidine

15 Which of the following is not a component of the nucleic acid backbone?

A Pentose sugar

B Phosphate group

C Nucleotide

D Phosphodiesterase bond

View Answer

Answer: Nucleotide

16 According to Chargaff’s rule the two strands of DNA has ___________

A Same molecular weight

B Same amount of A and G

C Different amount of A and G

D Different molecular weight

View Answer

Answer:Different molecular weight

17 In one strand of a double stranded DNA the rate of occurrence of A is 3 times C in consecutive 10 bases. So how many G will be there in 100 base pairs of a DNA duplex?[Consider G=T in one strand].

A 30

B 20

C 40

D 60

View Answer