Molecular Basis of Inheritance MCQs | Molecular Basis of Inheritance Multiple Choice Questions (MCQs) and Answers

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Questions
1 With respect to microsatellite DNA which of the following is correct?
A Tandem repeats
B Dinucleotide repeats
C 100 bp units
D Inaccurate duplicating

Answer:100 bp units
2 Genome – wide repeat unit are generally transposable elements.
A True
B False

Answer: True
3 Repeated DNA can be referred to as junk DNA.
A True
B False

Answer: False
4 The simpler the organism the more likely they are to have transposable elements.
A True
B False

Answer:False
5 Double-stranded structure of nucleic acid is the basic requirement for palindromic sequences.
A True
B False

Answer: True
6 Which of the following words represents a palindrome?
A DUCK
B MAMA
C BOOM
D MADAM

Answer:MADAM
7 Which of the following will form a palindromic sequence?
A ATTGCAAT
B AGTCCTGA
C GTTCCAAG
D GTTGGAAC

Answer: ATTGCAAT
8 Which of the following is affected by palindromic sequences?
A Acetylation site
B Phosphorylation site
C Methylation site
D Promoter site

Answer:Methylation site
9 Palindromic sequences play a very important role in gene manipulation.
A True
B False

Answer:True
10 Which of the following palindromes is not a restriction site?
A GAATTC
B TACGTA
C CCTAGG
D AGCT

Answer:TACGTA
11 Molecular cutters do not recognize the palindromic sequence.
A True
B False

Answer:False
12 Which of the following is an example of an inverted repeat?
A ATTCGCGAAT
B ATCGNNNNCGAT
C TACCNNNNGGAT
D AGCCNNNCCGA

Answer: ATCGNNNNCGAT
13 Inverted repeat have a number of biological functions. Which of the following is a biological function of an inverted repeat?
A Diseases
B Central dogma
C Cellular metabolism
D Genetic stability

Answer: Diseases
14 Most commonly known hairpin structures are found in _____________
A DNA
B mRNA
C tRNA
D rRNA

Answer: tRNA
15 Which of the following does not promote stability in stem-loop structure?
A Length of the stem
B Size of the loop
C A : U base pairing
D π orbital of aromatic ring

Answer:A : U base pairing
16 What is the minimum number of bases required for loop stability?
A 2
B 3
C 4
D 5

Answer:3
17 Which of the following does not contain a stem-loop structure?
A tRNA
B Pseudoknot
C Ribozyme
D rRNA

Answer:rRNA
18 Which of the following cannot be used for the separation of nucleic acids?
A SDS – PAGE
B PAGE
C Northern blotting
D PAGE

Answer:SDS – PAGE
19 The polymerization of the gel used in PAGE occurs between polyacrylamide and ____________
A N, N – acrylamide
B Bisacrylamide
C N – methyleneacrylamide
D N, N – methylene bisacrylamide

Answer: N, N – methylene bisacrylamide
20 If DNA is digested by endonucleases in four sites giving rise to fragments of which two are equal in length how many bands would be seen after electrophoresis?
A 3
B 4
C 5
D 6

Answer: 4

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